Background: Given the variations in clinical presentation and physiopathological mechanisms in irritable bowel syndrome (IBS) subtypes, it is an acknowledged fact that the response to treatments can be disparate. Objective: To assess the effect of vitamin D on inflammatory cytokines (IL-17, IL-10, TNF-α), and biomarkers of oxidative stress (total antioxidant capacity (TAC), and malondialdehyde ...

Introduction: Muscular inflammation and atrophy is one of the characteristics of diabetes that causes motor disability in these individuals. Studies have shown that exercise training with different intensities and the use of herbal drugs can have favorable effects on diabetes. The aim of this study was to interactive effects of continuous and interval training with crocin consu...

objective(s): tuberculosis is one of the most important infectious diseases with high mortality rates worldwide, especially in developing countries. interleukin17 (il-17) is an important acquired immunity cytokine, which is mainly produced by cd4+th17 cells. it can recruit neutrophils and macrophages to the infected site in the lungs. il-23 is one of the most important inducers of il-17. in the...

background: rheumatoid arthritis (ra) is a chronic, systemic, inflammatory disease with autoimmune etiology, characterized by synovial inflammation and destruction of joint cartilage and bone. there are controversial data about the profile of interleukin-17 (il-17a), interleukin-4 (il-4), and interferon-gamma (infî³), indicating in some studies the key role of il-17, while in others the th1 cyt...

OBJECTIVE To investigate the presence and role of interleukin-17 (IL-17) in rheumatoid arthritis (RA), and its regulation by antiinflammatory cytokines. METHODS The production of IL-17 was measured in supernatants of RA, osteoarthritis (OA), and normal synovial tissue pieces cultured ex vivo. Quantification of IL-17 was performed using a specific biologic assay. IL-17 gene expression was inve...

T helper (Th)17 cells producing interleukin (IL)-17 play a role in autoimmune and allergic inflammation. Here, we show that IL-23 induces IL-17 in the lung and IL-17 is required during antigen sensitization to develop allergic asthma, as shown in IL-17R-deficient mice. Since IL-17 expression increased further upon antigen challenge, we addressed its function in the effector phase. Most striking...