Aim. To investigate the associations of idiotypic IgA antibodies against benzo[a]pyrene, estradiol and progesterone (IgA 1 -Bp, IgA1 -E2, - Pg) with corresponding anti-idiotypic IgG to (IgG 2 -E2 -Pg) gene polymorphisms CYP1A1, CYP1A2, CYP1B1, CYP17A1, CYP19A1, GSTM1, GSTT1, GSTP1 in patients stage breast cancer. Materials Methods . Idiotypic serum 240 healthy women 505 cancer were measured by ...

BACKGROUND We recently developed a ddY mouse strain having high IgA levels (HIGA) that provided a murine model of IgA nephropathy. We additionally showed that administration of interleukin (IL)-12, a potent helper T (Th)1-inducing cytokine, induced an apparent reduction in serum IgA levels. In the present study, we assessed the influence of IL-12 administration on several physicochemical charac...

We extend the softFEM idea to isogeometric analysis (IGA) reduce stiffness (consequently, condition numbers) of IGA discretized problem. refer resulting approximation technique as softIGA. obtain discretization by first removing spectral outliers system’s stiffness. then add high-order derivative-jump penalization terms (with negative penalty parameters) standard bilinear forms. The parameter s...

In this study we investigated the agewise distributions of serum IgA concentrations in 1251 type 1 and 2224 type 2 diabetic patients, and the association between serum IgA concentration and diabetic complications (retinopathy, neuropathy, nephropathy, macroangiopathy, and hypertension). The IgA concentrations of all groups of diabetic patients were significantly higher than those of the corresp...

G. Rostoker, Department of Nephrology, INSERM U 139 and Fond d’Etudes du Corps médical H. Mondor, F-94010 Créteil (France) Sir, A possible relationship of primary IgA nephropathy (IgA GN) with wheat gliadin and latent celiac disease (CD) has been suggested by the presence of high levels of circulating IgA antigliadin antibodies [5], the decrease of IgA-containing circulating immune complexes af...

Mucosal IgA is important in local immune defence. Helicobacter pylori induces a specific IgA response in antral mucosa, but its immunopathology is unknown. Interleukin-8 (IL-8) has been suggested to be important in H. pylori-induced inflammation. Current information on the relationship between H. pylori-induced IgA and mucosal inflammation is limited. To investigate possible associations betwee...