The vast majority of children with idiopathic thrombocytopenic purpura, dramatic though their signs may be at presentation, remit within weeks, with or perhaps despite medical attention. Such children, when referred to the Queen Elizabeth Hospital, Hackney Road by their family doctor, or appearing in the busy casualty department, have a careful history taken with particular emphasis given to th...

Besides cytopenia related to treatment, several hematological disorders such as anemia, abnormal platelet activity, thrombosis, presence of anticardiolipin or anti-neutrophil antibodies, cyclic neutropenia, and myelodysplasia, have been reported in patients with Crohn's disease (CD). The case we report here is the first one documenting the association of idiopathic thrombocytopenic purpura (ITP...

Thirty-seven patients with idiopathic thrombocytopenic purpura (ITP) were treated with a standard Helicobacter pylori eradication regimen irrespective of H. pylori infection. Our results indicate that platelet recovery results from the disappearance of H. pylori itself, and is mediated, in part, through suppression of anti-platelet autoantibody production.

We report a case of autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura (Evans' syndrome) associated with gastric plasmacytoma. Recognition of this rare entity is important because surgery and chemotherapy together may achieve a cure. Possible mechanisms causing the hemolytic anemia and thrombocytopenia are discussed.

Thrombocytopenia of the type found in idiopathic thrombocytopenic purpura is described in a family with a deficiency of antihaemophilic factor, and a capillary abnormality. The propositus (father) has thrombocytopenia and abnormal platelet morphology, together with a plasma deficiency of antihaemophilic factor, but normal capillaries. His two daughters each are deficient in antihaemophilic fact...

Submucosal esophageal hematoma is an uncommon clinical entity. It can occur spontaneously or secondary to trauma, toxins, medical intervention, and in this case, coagulopathy. Management of SEH is supportive and aimed at its underlying cause. This article reports an 81-year-old male patient with chronic idiopathic thrombocytopenic purpura and hypertension that develops a submucosal esophageal h...