Background Autoimmunity may play a major role in the pathogenesis of idiopathic granulomatous mastitis (IGM). The therapeutic potential ozone therapy has recently been shown rheumatological diseases, and this study aimed to assess clinical efficacy (OT) refractory IGM. Methods Patients with biopsy-verified IGM incomplete response after steroid ( n = 47) between 2018 2021 were enrolled. Of these...