(109)Cd-based K-shell X-ray fluorescence spectrometry (hereafter, for brevity, XRF) is used, often in epidemiological studies, to perform non-invasive, in vivo measurements of lead in bone. We conducted the first interlaboratory study of XRF via the circulation of nine goat tibiæ in which the mean lead value ranged from 4.0 µg g(-1) to 55.3 µg g(-1) bone mineral. The test tibiæ were subsequentl...

The molecular structure of a variety of novel mercury-phytochelatin complexes was evidenced in rice plants exposed to inorganic mercury (Hg2+) using RP-HPLC with simultaneous detection via ICP-MS and ES-MS.

A low flow, parallel path Mira Mist CE nebulizer designed for capillary electrophoresis (CE) was evaluated as a function of make-up solution flow rate, composition, and concentration, as well as the nebulizer gas flow rate. This research was conducted in support of a project related to the separation and quantification of cobalamin (vitamin B-12) species using microseparation techniques combine...

We present a technique for the fast screening of the lead concentration in whole blood samples using laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS). The whole blood sample is deposited on a polymeric surface and wiped across a set of micro-grooves previously engraved into the surface. The engraving of the micro-grooves was accomplished with the same laser system used fo...

INTRODUCTION To estimate the long-term radiation dose to man due to artificial radionuclides, a detailed knowledge of their distribution in the environment is indispensable. From the viewpoint of toxicity and radiation damage to the human being, plutonium is by far the most important nuclide of the transuranic elements that has been released into the environment by nuclear weapons tests, satell...

PURPOSE To evaluate, in an experimental model, the reliability of MRI for determining whether a higher iron concentration was obtained in tumor tissue than in normal liver parenchyma after intra-arterial administration of Fe₃O₄ lipophilic nanoparticles. MATERIALS AND METHODS WAG/RijCrl rats were inoculated in the left hepatic lobe with 25,000 syngeneic CC-531 colon adenocarcinoma cells, after...

Particulate matter accumulated on tree bark specimens was examined in order to investigate its potential use as a natural monitor to study the impact on local atmospheric conditions. Tree bark from sargent cherry (Prunus sargentii) and sugar maple (Acer saccharum Marsh) trees was collected from four locations: Drax (North Yorkshire), Darley Dale (Derbyshire), Galway (Ireland) and Tristan da Cun...

An inductively coupled plasma mass spectrometer (ICP-MS) was used as a detector for gas chromatography (GC) and high performance liquid chromatography (HPLC) analysis of organotin compounds. ICP-MS is a highly sensitive detector with detection limits in the pg ng range, as well as enabling calibration by isotope dilution mass spectrometry (IDMS). Calibrating using isotopically labeled organotin...

Background: An inductively coupled plasma mass spectrometry (ICP-MS)-based immunoassay has been proposed independently by Baranov et al. (Anal Chem 2002;74:1629–36) and our group, but the applicability of this method for multianalyte analysis in clinical samples has not been fully illustrated. We developed a dual-label immunoassay method for the simultaneous determination of -fetoprotein (AFP) ...