A patient with multiple cystic hamartomas presented with a pneumothorax and later developed a cystic myxomatous vaginal polyp. This and three of the cysts were resected. She remains well 13 years later. Multiple cystic hamartomas are uncommon and may be misdiagnosed as pulmonary metastases.

Three cases are reported--one endobronchial hamartoma, one endobronchial hamartoma accompanied by a similar intrapulmonary lesion, and one multiple hamartoma. These cases typify the clinical presentation and illustrate some of the difficulties in diagnosis and management. The published cases are reviewed.

OBJECTIVES To evaluate the usefulness of power Doppler vocal fremitus (PDVF) breast sonography for differentiation of hamartomas from other breast (malign or benign) masses. MATERIAL AND METHODS Two hundred and six breast masses in 180 women were evaluated. The breast lesions were scanned first by mammography (MG), then by ultrasonography (US) with PDVF imaging. Finally, biopsy was performed ...

We have previously described in tuberous sclerosis (TSC) hamartomas the phenomenon of loss of heterozygosity (LOH) for DNA markers in the region of both the TSC2 gene on chromosome 16p13.3 and the TSC1 gene on 9q34. We now describe the spectrum of LOH in 51 TSC hamartomas from 34 cases of TSC. DNA was extracted from leucocytes or normal paraffin embedded tissue, and from frozen paraffin embedde...

Breast hamartoma is an uncommon, benign, slow-growing lesion found in all age groups after puberty. This pathological entity has a reported incidence of 1.2% of benign lesions and 4-8% of benign breast tumors in women (1, 2). It appears that with the increasing use of breast screening more hamartomas are likely to be identified. This rare pathological entity consists of a well-circum-scribed, b...

OBJECTIVE To review the entity of respiratory epithelial adenomatoid hamartoma of the paranasal sinuses using an illustrative case example of frontal sinus hamartoma. METHODS Case report with review of the literature. RESULTS Respiratory epithelial adenomatoid hamartoma represents a benign process that is generally cured with conservative surgical resection of the involved area. Nevertheles...

A 38 year old Saudi patient with tuberous sclerosis and chronic renal failure is described. The association of these two conditions has rarely been described. This case supports the observation that when chronic renal failure occurs in patients with tuberous sclerosis, cystic renal disease (with or without hamartomas) is more likely to be the underlying cause, rather than hamartomas alone.

Hamartomas are benign malformations composed of tissue elements normally found at that site, but which are growing in a disorganized fashion. Cutaneous hamartomas containing only neural and/or neurovascular elements are very rare, with very few case reports in the literature. Herein we describe a case of congenital neural angiomatous hamartoma of the skin.

The term ‘‘hamartoma’’ was first used by Albrecht in 1904 [1]. Hamartomas are defined as tumor-like, but primary nonneoplastic malformations or inborn errors of tissue development, characterized by an abnormal mixture of tissues indigenous to a part of the body with an excess of one or more of the cellular components [2]. It may occur in any organ of the body and are common in the spleen, liver...

Hypopharyngeal hamartomas are quite rare tumors that may cause nutritional or respiratory problems in neonates and infants. They may be confused with other benign laryngeal lesions. In this study a 7-month-old infant with congenital stridor and positional dyspnea caused by a hypopharyngeal hamartoma was reported with review of the literature. Hypopharyngeal hamartomas should be considered in th...