The patient was a 46-year-old woman, who was visited in our hospital because of progressive personality change, visual field defect, severe headache, and olfactory hallucination for the previous 3 months. On neurological examination, she had hyposmia and bitemporal hemianopia. Mini-mental status examination score was 28 out of 30. Furthermore, he had bilateral papilledema. Other neurological ex...

Decreased ability to smell results from a number of medical conditions, ranging from simple congestion of the nose to serious neurological disturbances. In this chapter I provide an overview of the olfactory dysfunctions present in several major neurological disorders and discuss current theories as to their cause. In some disorders, such as Alzheimer's disease and idiopathic Parkinson's diseas...

RATIONAL Kallmann syndrome (KS) is a genetic gonadotropin-releasing hormone deficiency associated with hyposmia or anosmia and characterized by various modes of inheritance. PATIENT CONCERNS A 16-year-old male did not reach puberty and was associated with hypogonadotropic hypogonadism and anosmia. His magnetic resonance imaging of brain revealed the absence of the olfactory bulb. DIAGNOSIS ...

Acinic cell carcinoma arising in nasal cavity is a rare entity, and the number of reported cases is very limited in the English-language literature. The diagnosis is based entirely on histological evaluations. We report a primary acinic cell carcinoma in a 63-year-old female who had right nasal obstruction with hyposmia for the past 2 years. The tumor was found to be arising from the right post...

A case of acute permanent anosmia is described in a renovation worker during exposure to a waterproof coating chemical. The chemical consisted of several substances of which four (acetone, acrylates, butyl acetate and carbon disulfide) has been previously reported to induce hyposmia or anosmia in workers. Other aetiologies were clinically excluded but a large arachnoidea cyst in the frontal par...

Introduction The extranasopharyngeal angiofibroma is histologically similar to juvenile nasopharyngeal angiofibroma, differing from the latter in clinical and epidemiologic characteristics. Objectives We present a case of extranasopharyngeal angiofibroma originating in the inferior turbinate. Resumed Report The patient was a girl, 8 years and 6 months of age, who had constant bilateral nasal ob...

Kallmann syndrome (KS) is a disease clinically characterized by the association of hypogonadotropic hypogonadism and anosmia or hyposmia, for which three modes of transmission have been described: X-linked, autosomal recessive and autosomal dominant. The KAL-1 gene, responsible for the X-linked form of the disease, has been isolated and its intron-exon organization determined. In this study, tw...