BACKGROUND Whether hypoglycemia leads to death in critically ill patients is unclear. METHODS We examined the associations between moderate and severe hypoglycemia (blood glucose, 41 to 70 mg per deciliter [2.3 to 3.9 mmol per liter] and ≤40 mg per deciliter [2.2 mmol per liter], respectively) and death among 6026 critically ill patients in intensive care units (ICUs). Patients were randomly ...

Abstract Nesidioblastosis is a very rare adult disorder in the absence of gastrointestinal surgery. endocrine pancreas causing hyperinsulinemic hypoglycemia. We describe case 83 year-old Caucasian male, with 3-year history severe refractory hypoglycemia glucose level below 2.1 mmol/L. Confusion and sleepiness were reported as his neuroglycopenic symptoms. According to family, symptoms improved ...

Background: Hypoglycemia is the commonest medical emergency in diabetic patients. It also most important limiting factor intensive control of diabetes. To find out frequency hypoglycemia Medical Emergency BIRDEM General Hospital.
 Materials and methods: This cross sectional observational study was done at Department Hospital, Dhaka, during period March, 2015 to November, 2015. Among patien...

BACKGROUND The number of elderly type 2 diabetes mellitus (T2DM) patients in Japan is increasing continuously. Hypoglycemia is a significant issue in their treatment. However, the actual situation and related details of their hypoglycemia remain unclear. In order to elucidate them, the Japan Physicians Association conducted a large-scale questionnaire survey for physicians and their outpatients...

While many studies have shown that intensive glycemic control can prevent the microvascular complications of diabetes, the benefits of intensive glycemic control in preventing macrovascular complications, including heart attacks, strokes, and overall mortality, have been less clear. Intensive glycemic control almost always increases the frequency and severity of hypoglycemic episodes. What rema...

Subcutaneous dasiglucagon (Zegalogue®), a next generation glucagon analog, is convenient and valuable addition to ready-to-use formulations for the rescue treatment of severe hypoglycemia in patients aged ? 6 years with diabetes. A single dose reverses insulin-induced typically within 10 min this population, without need additional intervention. The drug generally well tolerated, nausea vomitin...

Introduction: The term “reactive” hypoglycemia, also known as post-prandial hypoglycemia has been loosely defined in the literature. The term refers to the occurrence of autonomic symptoms including weakness, perspiration, hunger, nausea, anxiety and tremors occurring one to two hours after ingestion of a meal. This collection of symptoms has been described in various patient groups including p...

Iatrogenic hypoglycemia is the limiting factor in the glycemic management of diabetes (1,2). It causes recurrent morbidity in most people with type 1 diabetes as well as many with advanced type 2 diabetes and is sometimes fatal. It precludes maintenance of euglycemia over a lifetime of diabetes and, therefore, full realization of the benefits of glycemic control. It compromises physiological an...

G lycemic control remains a delicate balancing act. The diabetic patient is tasked with maintaining euglycemic blood glucose levels, a goal requiring education, decision strategies, volitional control, and the wisdom to avoid hyperand hypoglycemia, with the latter defined as plasma glucose less than 60 mg/dl. Glucose levels must be controlled continuously and without holidays. Failure to mainta...

We report the case of a 41-year-old woman with schizophrenia who developed persistent hypoglycemia following paliperidone administration. After discontinuing paliperidone, the hypoglycemia resolved, but symptoms of diabetes emerged. Therefore, it appears that the hypoglycemia induced by paliperidone may mask symptoms of diabetes. Paliperidone may induce hypoglycemia by increasing insulin secret...