OBJECTIVE The aim of this experimental study was to investigate whether hypertonic saline or sodium bicarbonate administration prevented the development of cardiotoxicity in rats that received toxic doses of amitriptyline. METHOD Thirty-six Sprague Dawley rats were used in the study. The animals were divided into six groups. Group 1 received toxic doses of i.p. amitriptyline. Groups 2 and 3 t...

Electrostatic interactions strongly affect the immersion depth of nanoparticles into an interface. We prove this statement by measuring the diffusion constant of charged nanoparticles at a sodium chloride solution/air interface. Interfacial diffusion of nanoparticles slows down with increasing ionic strength of the sodium chloride solution. Hydrodynamic calculations are used to estimate the imm...

Renal hemodynamics and the excretion rates of six ions were studied in a group of 24 normotensive and hypertensive subjects during expansion of extracellular fluid volume (ECF) with intravenous infusions of hypertonic saline. In response to the 2.5% saline infusions arterial blood pressure did not change from control values, but glomerular filtration rate increased, and renal vascular resistanc...

Introduction . Acute bronchiolitis (АB) is a common infection in children under the age of 2 years. In modern clinical protocols, routine use studied drugs not recommended. The effectiveness 3% hypertonic sodium chloride solution (HSCS) at vol. А im Тo study etiology, risk factors, therapy acute care intensive units (ICU), inhalations with HSCS hyaluronate (HS) comparison without inclusion this...

XALATAN Sterile Ophthalmic Solution (latanoprost ophthalmic solution) is supplied as a sterile, isotonic, buffered aqueous solution of latanoprost with a pH of approximately 6.7 and an osmolality of approximately 267 mOsmol/kg. Each mL of XALATAN contains 50 micrograms of latanoprost. Benzalkonium chloride, 0.02% is added as a preservative. The inactive ingredients are: sodium chloride, sodium ...

We have demonstrated that acute third ventricle injections of lead acetate (PbAc) exert a powerful antidipsogenic effect and induce a significant increase in renal sodium excretion. In the present study we confirm the antidipsogenic effect of lead and demonstrate that central administration of this metal, in minute amounts, significantly reduces salt intake both during dehydration and after cen...

We used in vivo perfusion of the lower intestine (colon plus coprodeum) to examine the osmoregulatory role of that organ in glaucous-winged gulls (Larus glaucescens Naum.) drinking sea water and fresh water. The area of the lower intestine was small, 0-59 cm 100g~' body mass. Its electrolyte and water transport rates were unaffected by salt water acclimation. Sodium and chloride were always rea...

OBJECTIVE To compare the efficacy of lacrimal probing and syringing among 3% solution of Sodium Chloride and/or 0.2 mg/ ml Mitomycin-C as an adjunctive medication. DESIGN A prospective, randomized, 2 by 2 factorial design study. MATERIAL AND METHOD Forty-eight of nasolacrimal duct obstruction patients with epiphora symptom were randomly assigned to receive either Normal Saline Solution or 3...

Ninety four children aged less than 5 years with diarrhoeal dehydration and acidosis were treated randomly with either World Health Organisation (WHO) oral rehydration solution containing sodium chloride, potassium chloride, sodium bicarbonate and glucose or an oral solution with tripotassium citrate monohydrate replacing the sodium bicarbonate and potassium chloride in the WHO solution. Fifty ...

It is generally believed that tears are required to furnish only oxygen to the corneal epithelium. However, as tears are a very complicated solution, it is likely that other factors are essential to the cells of the corneal surface. The amount of light scattered from the epithelial surface of the excised rabbit cornea was examined with the in vitro specular microscope while the epithelium was b...