Fetal outcome was evaluated in 157 hypertensive pregnant women whose underlying disease had been established by renal biopsy. The patients had pathologic diagnoses of preeclampsia (95), nephrosclerosis (23), nephrosclerosis with superimposed preeclampsia (13), interstitial and tubular nephropathy (seven), and normal findings (six). Pregnancy outcome in this selected group of patients was extrem...

To clarify the vascular endothelial function in pregnant women with hypertensive disorders, we assessed the flow-mediated vasodilation in the radial artery and compared it with plasma fibronectin levels. We determined flow-mediated vasodilation by measuring the change in radial artery diameter during hyperemia in 58 normal pregnant women, 22 preeclamptic pregnant women, and 15 pregnant women wi...

Severe pulmonary hypertensive diseases: a perspective. N.F. Voelkel, R.M. Tuder. #ERS Journals Ltd 1999. ABSTRACT: Clinically "severe pulmonary hypertension" is a group of diseases. The nomenclature of pulmonary hypertensive disorders is confusing since terms like "primary", "idiopathic", "unexplained" and "plexogenic" are often used interchangeably. In this Point of view or perspective the aut...

Practice Pointers Hypertensive disorders occur in up to 10% of pregnancies and are a major source of fetal and maternal morbidity and mortality.1 Although early recognition and treatment have improved some outcomes, the pathogenesis of preeclampsia spectrum disorders is still not well understood. The incidence of all hypertensive disorders of pregnancy is increasing in the United States, making...

Background. Progressive proteinuria indicates worsening of the condition in hypertensive disorders of pregnancy and hence its quantification guides clinician in decision making and treatment planning. Objective. To evaluate the efficacy of spot dipstick analysis and urinary protein-creatinine ratio (UPCR) in hypertensive disease of pregnancy for predicting 24-hour proteinuria. Subjects and Meth...

Disorders associated with hypertension during pregnancy, which are often linked with oedema and/or proteinuria and are variously termed toxaemia of pregnancy, EPH gestosis, pre-eclampsia, and eclampsia, are of unknown etiology, although they have been known for a long time and many attempts have been made to classify and explain them. In this paper, the author draws attention to the problems of...

Hypertensive Disorders in Pregnancy: Introduction Hypertensive disorders complicating pregnancy are common and form one of the deadly triad, along with hemorrhage and infection, that contribute greatly to maternal morbidity and mortality. In 2001, according to the National Center for Health Statistics, gestational hypertension was identified in 150,000 women, or 3.7 percent of pregnancies (Mart...

Hypertension during pregnancy has been classified by the American College of Obstetricians and Gynecologists into four distinct categories: (a) pre-eclampsia and eclampsia, (b) chronic hypertension (hypertension that was present before pregnancy), (c) chronic hypertension with superimposed preeclampsia or eclampsia, and (d) latent or transient hypertension of the third trimester (1). Most chron...

in 1996 grinspan et al presented the association between primary hypertension and diabetes mellitus as grinspan syndrome. through various studies, researchers have noticed that epidermal lichen planus cells show enzymatic disorders as well as defective carbohydrate expression. therefore, it was assumed that there is a relationship between cells and hormones in metabolic actions. besides, some r...