Background and Aim: We aimed to determine the prognostic imaging and clinical markers of chronic Post-Traumatic Sleep-Wake Disorders (PTSWDs) with a special focus on the early cognitive and executive dysfunctions following Traumatic Brain Injury (TBI). The prevalence rate of Post-Traumatic Psychiatric Disorders (PTPDs) in various sleep disorders was also investigated. Methods and Materials/Pat...

M. Engström, T. Karlsson, and A-M. Landtblom IMH/Radiological Sciences/CMIV, Linköping University, Linköping, Sweden, Behavioural Sciences and Learning/CMIV, Linköping University, IKE/Neurology/CMIV, Linköping University Introduction The Kleine–Levin Syndrome (KLS) is a rare but relatively well-defined disorder characterised by excessive sleep periods (periodic hypersomnia) associated with beha...

1. Modafinil, a putative central alpha 1 adrenergic agonist, was tested in idiopathic hypersomnia and narcolepsy. 2. Sleep attacks and drowsiness were significantly decreased in 83% of 18 hypersomniac subjects and 71% of 24 narcoleptics. 3. When cataplectic episodes were not totally suppressed the association of a low dose of Clomipramine was successful in improving them. 4. Modafinil, used for...

We examined sleep difficulties preceding death in a sample of adolescent suicide completers as compared with a matched sample of community control adolescents. Sleep disturbances were assessed in 140 adolescent suicide victims using a psychological autopsy protocol and in 131 controls using a similar semi-structured psychiatric interview. Rates of sleep disturbances were compared between groups...

BACKGROUND Aircraft noise is a major environmental noise problem. This study was conducted in order to investigate the relationship between sleep disturbance and exposure to aircraft noise on the residents who are living near an airport. METHODS There were 3308 residents (1403 in the high exposure group, 1428 in the low exposure group, and 477 in the non-exposure group) selected as the subjec...

This study investigated gender differences in symptom profiles of major depressive disorder (MDD) in the Korean general population. Data were pooled from the series of nationwide Korean Epidemiologic Catchment Area surveys conducted in 2001, 2006 and 2011, respectively. Of the 18,807 participants, 507 (397 women and 110 men) were diagnosed with MDD within the prior 12 months. In agreement with ...

BACKGROUND Modafinil is a well-tolerated psychostimulant drug with low addictive potential that is used to treat patients with narcolepsy and other excessive sleepiness. Whereas favorable effects of modafinil on cognitive functions have been shown in a large number of studies, there are very few reports presenting the effects of modafinil electrophysiologically. The aim of this study was to inv...

Kleine-Levin syndrome (KLS) was first described in 1862 by Brierre de Boismont and gained its eponymous name from the reports of Willi Kleine (1) and Max Levin (2) in the 1920s. It is a rare disorder that occurs worldwide and is characterised by episodes of sleep, behavioural, mood and cognitive disturbance, with usually an onset in adolescence and a variable episodic course. The focus on hyper...

One definition of atypical depression has emphasized the reversed vegetative symptoms (hypersomnia and hyperphagia) (Aarons et al 1985) in the context of a nonendogenous (or mood reactive) depressive state (Ravaris et al 1980). This clinical picture overlaps with Seasonal Affective Disorder (SAD) (Rosenthal et ai 1984), which is a syndrome of recurrent depressions associated with fatigue, hyper...

We examined sleep difficulties preceding death in a sample of adolescent suicide completers as compared with a matched sample of community control adolescents. Sleep disturbances were assessed in 140 adolescent suicide victims with a psychological autopsy protocol and in 131 controls with a similar semistructured psychiatric interview. Rates of sleep disturbances were compared between groups. F...