Optimal gene therapy for cancer must (i) deliver DNA to tumor cells with high efficiency, (ii) induce minimal toxicity, and (iii) avoid gene expression in healthy tissues. To this end, we generated a library of >500 degradable, poly(beta-amino esters) for potential use as nonviral DNA vectors. Using high-throughput methods, we screened this library in vitro for transfection efficiency and cytot...

Polyethyleneimine (PEI)-coated slides were used for attachment of unknown extremophiles and their cultures grown at high temperature and low pH. Selective adhesion of cells in natural samples and cultural isolates was compared to polylysine (PL) and several other coatings. PEI is superior to PL for adhesion of extremophiles.

We report a branched polyethyleneimine (BPEI)-quantum dot (QD) based rewritable fluorescent system with a multicolor recording mode, in which BPEI is both QD-multicolor patterning "writer" and data erasing "remover". This method could write distinct colors from size-tailored QDs to represent large numbers of logic states for high data storage capacity.

The objective of this study was to investigate the behavior of highly functional acrylates, during isothermal ultraviolet (UV) curing. The materials included a penta-functional acrylate and two acrylated hyperbranched polymers, one with a stiff polyester core and one with a more flexible polyether core. In particular, the influence of UV intensity and reactive blend composition on structural tr...

A new bacteria microarray patterning technique is developed by patterning thick polycationic polymers on glass surface, which generates high-coverage and high-precision E. coli cell patterns. Cell immobilization efficiency is greatly improved, compared to conventional monolayer surface patterning approach. Cell viability tests show very low cytotoxicity of polyethyleneimine (PEI). This advancem...

In this study, hyperbranched polymers were explored as matrix modifiers to create E-glass fiber (GF) reinforced polymer composites with enhanced mechanical properties. Hyperbranched have lower viscosities than their linear equivalents, potentially providing wet out leading improved stress transfer. (HB), hydrogenated (H-HB), and functional (LF) divinyl benzene blended polystyrene (LP) form a ra...