نتایج جستجو برای: hydrophilic

تعداد نتایج: 15369  

Journal: :Neurourology and urodynamics 2011
Emmanuel Chartier-Kastler Pierre Denys

AIMS Neurogenic bladder can be effectively managed with intermittent catheterization (IC) to improve or restore continence, but there is no consensus on which type of catheter is preferred. Hydrophilic catheters were developed to reduce urethral friction, thereby minimizing trauma and sticking, and making them more acceptable to the patient, and easier and safer to use. The objective of this ar...

Journal: :Organic & biomolecular chemistry 2017
Din-Chi Chiu Tzu-Chen Lin Wen-I Huang Ting-Jen Cheng Keng-Chang Tsai Jim-Min Fang

Peramivir is an effective anti-influenza drug in the clinical treatment of influenza, but its efficacy toward the H275Y mutant is reduced. The previously reported cocrystal structures of inhibitors in the mutant neuraminidase (NA) suggest that the hydrophobic side chain should be at the origin of reduced binding affinity. In contrast, zanamivir having a hydrophilic glycerol side chain still pos...

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