BACKGROUND In the face of changing environmental conditions, the mechanisms underlying stress responses in diverse organisms are of increasing interest. In vertebrates, Drosophila, and Caenorhabditis elegans, FoxO transcription factors mediate cellular responses to stress, including oxidative stress and dietary restriction. Although FoxO genes have been identified in early-arising animal lineag...

Developmental processes such as morphogenesis, patterning and differentiation are continuously active in the adult Hydra polyp. We carried out a small molecule screen to identify compounds that affect patterning in Hydra. We identified a novel molecule, DAC-2-25, that causes a homeotic transformation of body column into tentacle zone. This transformation occurs in a progressive and polar fashio...

Data quality monitoring is critical to all experiments impacting the of any physics results. Traditionally, this done through an alarm system, which detects low level faults, leaving higher human crews. Artificial Intelligence beginning find its way into scientific applications, but comes with difficulties, relying on acquisition new skill sets, either education or acquisition, in data science....

The dynamics of boundary regions have been investigated mainly by axial grafting and with the emphasis on the head end. The time to resist inhibition of head-end formation and the ability to inhibit head-end formation have been assayed under a variety of conditions. The times increase with distance from the head end. The times required by a boundary region to aquire the inhibitory properties of...

We give examples of CAT(0), biautomatic, free–by–cyclic, one–relator groups which have finite–rank free subgroups of huge (Ackermannian) distortion. This leads to elementary examples of groups whose Dehn functions are similarly extravagant. This behaviour originates in manifestations of Hercules–versus–the–hydra battles in string– rewriting. 2010 Mathematics Subject Classification: 20F65, 20F10...