Point spread function (PSF) phantoms based on unstructured distributions of sub-resolution particles in a transparent matrix have been demonstrated as a useful tool for evaluating resolution and its spatial variation across image volumes in optical coherence tomography (OCT) systems. Measurements based on PSF phantoms have the potential to become a standard test method for consistent, objective...

In proton density-weighted (PDW) MR imaging, the patterns of signal intensity vary depending on the imaged material, and change with the flip angle (FA) applied to the imaged material. The correlation between the pre-determined FA and the actual FA applied to imaged objects was investigated using 4 types of phantoms having different dielectric properties. PDW images were acquired using the spin...

We introduce new realistic three-dimensional tissue phantoms which can help to understand the optical properties of human epithelium as well as the optical signatures associated with the dysplasia to carcinoma sequence. The phantoms are based on a step by step multilayer reconstitution of the epithelial tissue using main components characteristic for the human epithelium. Each consecutive step ...

irk J. Faber niversity of Amsterdam cademic Medical Center epartment of Biomedical Engineering and Physics and pththalmology Department msterdam, 1100 DE Netherlands Abstract. Current innovations in optical imaging, measurement techniques, and data analysis algorithms express the need for reliable testing and comparison methods. We present the design and characterization of silicone elastomer-b...

Introduction: Long-term teletherapy program is not suitable for old and working patients and those living in areas where little access to primary health care is available. Accelerated partial breast irradiation (APBI) using high dose rate (HDR) brachytherapy is an appropriate alternative for these patients due to its limited number of fractions. The AccuBoost is a system for delivering APBI. Th...

In computed tomography (CT), the noise is sometimes non-uniform, i.e. magnitude may vary with gradient level within image. The purpose of this study was to quantify non-uniformity in CT images using appropriate 1D and 2D computational phantoms, validate effectiveness proposed concept filtered by bilateral filter (BF), as an example a non-linear filter. We first developed Gaussian noises several...

The Food and Drug Administration (FDA) is conducting research on developing reference lung cancer lesions, called phantoms, to test computed tomography (CT) scanners and their software. FDA loaned two semi-spherical phantoms to the National Institute of Standards and Technology (NIST), called Green and Pink, and asked to have the phantoms' volumes estimated. This report describes in detail both...

We present a technique for fabricating realistic breast phantoms for microwave imaging experiments. Using oil-in-gelatin dispersions that mimic breast tissue dielectric properties at microwave frequencies, we constructed four heterogeneous phantoms spanning the full range of volumetric breast densities. We performed CT scans and dielectric properties measurements to characterize each phantom.

In this paper, we describe the procedures to make epoxy resin and agarose phantoms designed using Mie scattering calculations. The phantoms are constructed to be used in the estimation of point spread function (PSF) of an optical coherence tomography (OCT) and evaluation of optical properties extraction (OPE) algorithm.

Optical phantoms are used in the development of various imaging systems. For certain applications, the development of thin phantoms that simulate the physical size and optical properties of tissue is important. Here, we demonstrate a method for producing thin phantom layers with tunable optical properties using poly(dimethylsiloxane) (PDMS) as a substrate material. The thickness of each layer (...