Since most knowledge about protein-protein interactions still hides in biological publications, there is an increasing focus on automatically extracting information from the vast amount of biological literature. Existing approaches can be broadly categorized as rule-based or statistically-based. Rule-based approaches require heavy manual effort. On the other hand, statistically-based approaches...

Herpesvirus saimiri (HVS), a T-lymphotropic tumor virus of neotropical primates, and the Kaposi's sarcoma-associated human herpesvirus 8 (KSHV) belong to the gamma-(2)-herpesvirus (Rhadinovirus) subfamily and share numerous features of genome structure and organization. The KSHV latency-associated nuclear antigen (LANA) protein appears to be relevant for viral persistence, latency, and transfor...

We aimed to assess the intestinal colonization dynamics by multiple extended-spectrum cephalosporin-resistant Enterobacteriaceae (ESC-R-Ent) clones in Swiss travelers to India, a country with high prevalence of these multidrug-resistant pathogens. Fifteen healthy volunteers (HVs) colonized with ESC-R-Ent after traveling to India who provided stools before, after, and at 3- and 6-month follow-up...

PURPOSE Cited2 (CBP/p300-interacting transactivators with glutamic acid (E) and aspartic acid (D)-rich tail 2) is a member of a new family of transcriptional modulators. Cited2 null embryos exhibit hyaloid hypercellularity consisting of aberrant vasculature in the eye. The purpose of the study is to address whether abnormal lenticular development is a primary defect of Cited2 deletion and wheth...

High voltage stimulation (HVS) allows supramaximal stimulation of proximal peripheral nerves down to the nerve roots and the plexus, thus making them accessible to neurographic investigation. In particular, useful information can be obtained in this manner with respect to demyelinating disorders of peripheral nerves. For that purpose, this article shows practical application of HVS and moreover...

In the first two articles, the author reports on research exploring the attitudes towards, and knowledge and experience of, caring for patients with breast cancer of health visitors (HVs) acting as resource personnel for colleagues. The study also examined how they used their knowledge and what difference it made to patients' coping ability at various stages of the disease. The HVs underwent a ...

We propose a hybrid generative/discriminative framework for semantic parsing which combines the hidden vector state (HVS) model and the hidden Markov support vector machines (HMSVMs). The HVS model is an extension of the basic discrete Markov model in which context is encoded as a stack-oriented state vector. The HM-SVMs combine the advantages of the hidden Markov models and the support vector ...

The human visual system (HVS) has a limited sensitivity in perceiving visual information such that visual masking estimation is helpful to improve the performance of image processing techniques. Most existing research efforts only focus on the methods of assessing the visual masking for gray images. In this paper, a spatial masking estimation utilizing the free-energy principle to measure just ...

BACKGROUND We previously observed impaired habituation mechanisms of the conventional blink reflex (BR) in patients with episodic cluster headache (ECH) during the bout, studying only the affected side. Here, we have studied the nociceptive-specific BR (nBR) both on the affected and non-affected sides, and in relation to clinical features. PARTICIPANTS AND METHODS We recorded nBR in 18 ECH pa...

Human visual system (HVS) models have been used in digital watermarking to minimize the visual effects of the watermark while increasing the strength of watermark. Such work has been applied to different watermarking schemes with varying degrees of success. Previous work at Digimarc resulted in a HVS model that inserts a high watermark signal in busy or high contrast areas, while reducing the w...