Previous work has shown that versican, decorin and a catabolic fragment of decorin, termed decorunt, are the most abundant proteoglycans in human skin. Further analysis of versican indicates that four major core protein species are present in human skin at all ages examined from fetal to adult. Two of these are identified as the V0 and V1 isoforms, with the latter predominating. The other two s...

In vitro testing of drugs with excised human skin is a valuable prerequisite for clinical studies. However, the analysis of excised human skin presents several obstacles. Ongoing drug diffusion, microbial growth and changes in hydration state influence the results of drug penetration studies. In this work, we evaluate freeze-drying as a preserving preparation method for skin samples to overcome...

abstract background: geographical health research examines the effect of environmental factors on human health examines. the environment where human and nature both is greatly influenced by the climatic conditions. the types of skin cancer world wide as well as iran are among the most common diseases and according to studies, are influenced by environmental factors . the objective here is to an...

In vitro percutaneous absorption of four antihypertensive drugs were carried out across the mice and human cavader skin in order to compare their skin permeability. An interesting trend was noticed in these experiments. Poorly water soluble drug prazosin hydrochloride showed 13 times enhanced flux in the mice skin whereas the steady-state flux of the water soluble drug propranolol hydrochloride...

The extraction of the skin pixels in a human image and rejection of non-skin pixels is called the skin segmentation. Skin pixel detection is the process of extracting the skin pixels in a human image which is typically used as a pre-processing step to extract the face regions from human image. In past, there are several computer vision approaches and techniques have been developed for skin pixe...

The efficient human skin detection method is more suitable for many human skin colors with different illumination conditions which is used to skin segmentation. There are many human skin –color detection methods were available but they were not performing efficient with different ethnic. These are algorithm is based on skin colour detection. One of the problems this and similar algorithms have ...

Human skin not only serves as an important barrier against the penetration of exogenous substances into the body, but also provides a potential avenue for the transport of functional active drugs/reagents/ingredients into the skin (topical delivery) and/or the body (transdermal delivery). In the past three decades, research and development in human skin equivalents have advanced in parallel wit...