OBJECTIVES It is important to control the quality level of the observational studies in conducting meta-analyses. The Newcastle-Ottawa Scale (NOS) is a representative tool used for this purpose. We investigated the relationship between high-quality (HQ) defined using NOS and the results of subgroup analysis according to study design. METHODS We selected systematic review studies with meta-ana...

The order-q Tsallis (Hq ) and Rényi entropy (Kq ) receive broad applications in the statistical analysis of complex phenomena. A generic problem arises, however, when these entropies need to be estimated from observed data. The finite size of data sets can lead to serious systematic and statistical errors in numerical estimates. In this paper, we focus upon the problem of estimating generalized...

Hydroquinone (HQ) is a chemical compound that inhibits the functions of melanocytes and has long been known for its skin-whitening effect. According to previous studies, the Tyrosinase (Tyr) activity inhibitory effect and melanocyte-specific cell toxicity are known depigmenting mechanisms; however, details of the underlying mechanisms are unknown. Arbutin (Arb) is also known for its Tyr activit...

Background. Multiple modalities have been used in the treatment of melasma with variable success. Niacinamide has anti-inflammatory properties and is able to decrease the transfer of melanosomes. Objective. To evaluate the therapeutic effect of topical niacinamide versus hydroquinone (HQ) in melasma patients. Patients and Methods. Twenty-seven melasma patients were randomized to receive for eig...

The M⋯HO axial interaction in the isoleptic and isoelectronic square-planar compounds [(CF3)3Pt(hq)]− (CF3)3Au(hq) turns from attractive (M = Pt) to repulsive Au), evidencing ligand-field inversion when going Pt Au.

eXtension (pronounced e-extension) is an online resource transforming how faculty can collaborate and deliver equine education. As the first Community of Practice launched from eXtension, HorseQuest (HQ) offers free, interactive, peer-reviewed, online resources on a variety of equine-related topics at http://www.extension.org. This group has adapted traditional educational content to the online...

BACKGROUND Apoptosis is a hallmark of beta-cell death in both type 1 and type 2 diabetes mellitus. Understanding how apoptosis contributes to beta-cell turnover may lead to strategies to prevent progression of diabetes. A key mediator of apoptosis, mitochondrial function, and cell survival is apoptosis inducing factor (AIF). In the present study, we investigated the role of AIF on beta-cell mas...

Hydroquinone (HQ) was electrochemically measured using convolutive cyclic voltammetry and differential pulse (DPV) on a nano-architecture mesoporous platinum film grown from hexagonal liquid crystalline template of C16EO8 surfactant in 1.0 mol/l HClO4. The HQ voltammograms produced one oxidative peak the forward sweep potential reductive reverse sweep. effect concentration investigated differen...

This study was envisaged to explore the impact of pesticide solid waste leachate to Allium cepa (common onion) bulbs. Bulbs exposed to the leachate showed hampered root growth and morphological deformities. At 15% and higher concentrations of leachate after 5 days, gall like swellings were noticed around the mitotic zone (zone of root growth). From the dose response curve, the EC50 values for t...

8-Hydroxyquinoline (HQ) chelates Mg2+ and Mn2+ and, secondarily, affects the activities of DNA and RNA polymerases. The in vivo effect of HQ has been estimated in Allium cepa L. meristems growing under new growth kinetics in the presence of this agent. HQ (at both 5 X 10(-5) M and 10(-4) M) depressed incorporation of [3H]uridine much more effectively than that of [3H]-thymidine. Cycle kinetics ...