نتایج جستجو برای: hpmc k100m

تعداد نتایج: 1285  

2017
Yuxia Zhang Yan Bai Huali Chen Yuanrui Huang Pei Yuan

A colon-specific capsule with alginate beads containing a self-microemulsifying drug delivery system (SMEDDS) was developed and evaluated. The SMEDDS technique was used to improve the solubility of curcumin (Cur). After encapsulating the Cur-loaded SMEDDS, the alginate beads were placed inside an impermeable capsule body. A konjac glucomannan/lactose/hydroxypropyl methylcellulose (KG/Lac/ HPMC)...

2015
S. Lefnaoui

The aim of this work was to investigate the effects of the nature and concentration of cellulose derivatives on the release kinetics of ibuprofen from hydrogel matrices using a response surface method (RSM). A series of cellulose derivatives, as methyl, hydroxyethyl, hydroxypropyl and hydroxypropyl methyl celluloses (MC, HEC, HPC and HPMC) were used as polymer platforms and their impacts on dru...

2016
Shih-Chen Shi Chieh-Chang Su

The corrosion inhibition characteristics of the derivatives of biopolymer hydroxypropyl methylcellulose (HPMC), hydroxypropyl methylcellulose phthalate (HPMCP), and hydroxypropyl methylcellulose acetate succinate (HPMCAS) film are investigated. Based on electrochemical impedance spectroscopic measurements and potentiodynamic polarization, the corrosion inhibition performance of high speed steel...

2011
B. S. Kapoor G. V. Subbarao

Itraconazole is practically insoluble in water; large interindividual and intra-individual variations of its oral bioavailability are reported. The main purpose of this study was to prepare and evaluate itraconazole granules for immediate release as drug delivery formulations. As a part of formulation optimization, different concentrations of hydroxypropyl-methyl cellulose (HPMC) E5 were taken ...

2013
Rajendra Pal S. Rathore Chetan S. Chauhan Rajesh K. Nema Manohar S. Dulawat

Ketoprofen is a potent non-steroidal anti-inflammatory drug which is used for the treatment of rheumatoid arthritis. The oral administration of ketoprofen can cause gastric irritation and renal adverse effects. Topical application of the drug can bypass gastrointestinal disturbances and provide relatively consistent drug levels at the site of action. Since the efficacy of gels depends on the ty...

Journal: :Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2006
Sajeev Chandran Punnarao Ravi Ranendra N Saha

The objective of this study was to develop controlled release matrix embedded formulations of celecoxib (CCX) as candidate drug using hydroxy propyl methyl cellulose (HPMC) and ethyl cellulose (EC), either alone or in combination, using optimization techniques like polynomial method and composite design. This would enable development of controlled release formulations with predictable and bette...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد علوم دارویی - دانشکده داروسازی 1393

بیماریهای قلبی –عروقی شایع ترین علت مرگ در دنیا هستند.متوپرولول تارترات یک بتا بلاکر اختصاصی است که دربیماریهای قلبی –عروقی مورد استفاده قرار می گیرد.هدف ازاین تحقیق فرمولاسیون متوپرولول تارترات آهسته رهش ماتریکسی ،برای استفاده در فشار خون سرخرگی وبیماریهای ایسکمیک می باشد. در این بررسی قرص های آهسته رهش ماتریکسی متوپرولول تارترات با روش گرانولاسیون مرطوب و بااستفاده از پلیمر hpmc 4000cps و صمغ...

Journal: :Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2008
Yellela S Krishnaiah Saleh M Al-Saidan

OBJECTIVE To study the in vitro transdermal permeation of trimetazidine from hydroxypropylmethyl cellulose (HPMC) gel drug reservoir system using nerodilol as a penetration enhancer. MATERIALS AND METHODS An HPMC gel containing selected concentrations of nerodilol (0, 2, 4 or 5% w/v) and 2.5% w/v of trimetazidine was prepared, and subjected to in vitro permeation studies across rat epidermis....

2015
Samy Yassin Ke Su Hungyen Lin Lynn F Gladden J Axel Zeitler

Tablet dissolution is strongly affected by swelling and solvent penetration into its matrix. A terahertz-pulsed imaging (TPI) technique, in reflection mode, is introduced as a new tool to measure one-dimensional swelling and solvent ingress in flat-faced pharmaceutical compacts exposed to dissolution medium from one face of the tablet. The technique was demonstrated on three tableting excipient...

2010
Christopher J Moulton Rudy J Valentine Donald K Layman Suzanne Devkota Keith W Singletary Matthew A Wallig Sharon M Donovan

Breast cancer is the most prevalent cancer in American women. Dietary factors are thought to have a strong influence on breast cancer incidence. This study utilized a meal-feeding protocol with female Sprague-Dawley rats to evaluate effects of two ratios of carbohydrate:protein on promotion and early progression of breast tissue carcinomas. Mammary tumors were induced by N-methyl-N-nitrosourea ...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید