نتایج جستجو برای: hodgkin lymphomas

تعداد نتایج: 37471  

Journal: :Hematology. American Society of Hematology. Education Program 2006
Steven T Rosen Christiane Querfeld

Primary cutaneous T-cell lymphomas (CTCLs) encompass a clinically and biologically heterogeneous group of non-Hodgkin lymphomas (NHLs) defined by clonal proliferation of skin-homing malignant T lymphocytes and natural killer cells. They account for up to 75% to 80% of all cutaneous lymphomas. The current WHO-EORTC classification of cutaneous lymphomas with primary cutaneous manifestations lists...

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Journal: :American journal of clinical pathology 2004
Maria B G Costa Sheila A C Siqueira Paulo H N Saldiva Klaus F Rabe Thais Mauad

Secondary lung infiltration by lymphomas occurs frequently. To our knowledge, however, no recent studies have attempted to discriminate histologic patterns of lung infiltration in the lymphoma subtypes. We retrospectively evaluated the frequency of lung infiltration and the respective infiltration patterns by lymphomas at autopsy, during an 11-year period. Lymphomas were classified according to...

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Journal: :international journal of hematology-oncology and stem cell research 0
zohreh sanaat associate professor of hematology-oncology, hematology-oncology research center, tabriz university of medical science, tabriz, iran. seyed-mohammad tavangar professor of pathology, pathology department, shariati hospital, tehran university of medical science, tehran, iran. jalil vaez gharamaleki professor of hematology-oncology, hematology-oncology research center, tabriz university of medical science, tabriz, iran. iraj aswadi kermani professor of hematology-oncology, hematology-oncology research center, tabriz university of medical science, tabriz, iran. jamal eivazi ziae associate professor of hematology-oncology, hematology-oncology research center, tabriz university of medical science, tabriz, iran. alireza nikanfar associate professor of hematology-oncology, hematology-oncology research center, tabriz university of medical science, tabriz, iran.

background: lymphomas are a group of malignancies affecting b, t and nk cells. cox-2 enzyme is one of the known inflammatory factors which increase in the inflammation process. increase in cox-2 expression inhibits apoptosis and increases tumor cells invasion and angiogenesis. increase in the cox-2 gene expression is seen in a group of cancers .specific cox-2 inhibition also can be beneficial i...

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Journal: :British journal of haematology 2014
Jorge J Castillo John L Reagan Kenneth D Bishop Emmanuel Apor

The association between viruses and lymphomas has long been recognized; however, the pathophysiological phenomena behind this relationship are unclear, and have been the object of intense research. Although our understanding of such mechanisms is slowly improving, much is still left to learn. With the recent advances in cancer biology, a diversity of biological pathways and novel targets and ag...

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2017
Liron Pantanowitz Bruce J. Dezube

Salivary gland enlargement, most commonly involving one or both parotid glands, is sometimes seen in association with HIV infection. Enlargement of the parotid gland may be due to diffuse infiltrative lymphocytosis syndrome; lymphoepithelial cysts; or malignant tumors, such as squamous cell carcinoma, Kaposi sarcoma, and Hodgkin and non-Hodgkin lymphomas.1,2 Non–HIV-related causes of parotid en...

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2011

Non-Hodgkin diffuse large B-cell lymphomas of the mastoid that extend from the nasopharynx are extremely rare in children. Moreover, in lymphoproliferative diseases, the presence of otoneurological signs prior to systemic disease involvement is rare. Here, we present a rare case of non-Hodgkin B-cell lymphoma invading the middle ear and mastoid in a 1-year-old boy that mimicked acute mastoiditi...

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Journal: :ORL; journal for oto-rhino-laryngology and its related specialties 2011
Sho Kanzaki Hideyuki Saito Tetsuya Mori Noriko Shimasaki Makio Mukai Kaoru Ogawa

Non-Hodgkin diffuse large B-cell lymphomas of the mastoid that extend from the nasopharynx are extremely rare in children. Moreover, in lymphoproliferative diseases, the presence of otoneurological signs prior to systemic disease involvement is rare. Here, we present a rare case of non-Hodgkin B-cell lymphoma invading the middle ear and mastoid in a 1-year-old boy that mimicked acute mastoiditi...

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2013
Muhammed Akıl Avni Kaya M.Selçuk Bektaş Fesih Aktar Sinan Akbayram Salim Bilici Mehmet Beyazal

Burkitt’s lymphomas or their variants (approximately 40% of non-Hodgkin lymphomas) seen in child age. Sporadic Burkitt’s lymphoma is most common involvement in the abdomen. Approximately 25%-30% of children are develop acute abdomen due to the right lower quadrant mass or ileo-cecal invagination. The initial presentation of disease occurs are abdominal pain, nausea, vomiting, gastrointestinal b...

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Journal: :Annals of clinical and laboratory science 2007
Carl L Buckner Lydia R Christiansen Danyel Bourgeois John J Lazarchick John Lazarchick

Mature T-cell neoplasms are relatively uncommon, accounting for approximately 10% of all non-Hodgkin lymphomas. This category of hematopoietic neoplasms is clinically aggressive and shows a poor response to therapy and shortened survival. The antigen CD20 has long been thought to be a specific marker for B-cell lineage and has been used to help differentiate T-cell and B-cell neoplasms. We pres...

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Journal: :Proceedings of the National Academy of Sciences of the United States of America 2017
Francesco Abate Ana C da Silva-Almeida Sakellarios Zairis Javier Robles-Valero Lucile Couronne Hossein Khiabanian S Aidan Quinn Mi-Yeon Kim Maria Antonella Laginestra Christine Kim Danilo Fiore Govind Bhagat Miguel Angel Piris Elias Campo Izidore S Lossos Olivier A Bernard Giorgio Inghirami Stefano Pileri Xosé R Bustelo Raul Rabadan Adolfo A Ferrando Teresa Palomero

Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of non-Hodgkin lymphomas frequently associated with poor prognosis and for which genetic mechanisms of transformation remain incompletely understood. Using RNA sequencing and targeted sequencing, here we identify a recurrent in-frame deletion (VAV1 Δ778-786) generated by a focal deletion-driven alternative splicing mechanism as well ...

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