INTRODUCTION Renal involvement is the major cause of mortality and morbidity in children with Henoch-Schonlein purpura. The purpose of this study was to determine the predictive factors of Henoch-Schonlein nephritis (HSN) and correlations between clinical and pathologic findings. MATERIALS AND METHODS Demographic characteristics and clinical manifestations of 105 children with Henoch-Schonlei...

Kidney transplantation (Ktx) is generally performed during end stage renal disease due to a loss of the kidneys' ability to filter wastes from the circulatory system. Acute graft-versus-host disease (GVHD) after Ktx is a life-threatening complication that progresses to organ failure, systemic complications, and death. The current study evaluated the significance of histologic findings of GVHD a...

BACKGROUND AND PURPOSE Current classification and grading of primary brain tumors has significant limitations. Our aim was to determine whether the relative cerebral volume (rCBV) measurements in gliomas may serve as an adjunct to histopathologic grading, with a hypothesis that rCBV values are more accurate in predicting 1-year survival and recurrence. MATERIALS AND METHODS Thirty-four patien...

PURPOSE: The 5-year survival rates of head and neck squamous cell carcinomas (HNSCC) remain disappointing. HNSCCs develop in precursor fields of genetically altered cells that are often not completely resected when the tumor is excised, causing local relapse. These precursor fields are mostly recognized as dysplasia, but histologic grading cannot reliably predict malignant transformation. Our a...

background diffusion-weighted imaging (dwi) is a form of magnetic resonance imaging (mri) based on measuring the random brownian motion of water molecules within the biological tissues and is particularly useful in tumor characterization. objectives the purpose of this study was to evaluate the diagnostic value of dw mri and the apparent diffusion coefficient (adc) for preoperative grading of a...

BACKGROUND Response to preoperative radiochemotherapy (RCT) in patients with locally advanced rectal cancer is very heterogeneous. Pathologic complete response (pCR) is accompanied by a favorable outcome. However, most patients show incomplete response. The aim of this investigation was to find indications for risk stratification in the group of intermediate responders to RCT. METHODS From a ...