OBJECTIVE CT-P13 is a biosimilar with comparable pharmacokinetics, efficacy and safety to its reference product (RP), infliximab. Studies have shown that switching from RP to CT-P13 does not reduce the effectiveness or safety of treatment. METHODS In this retrospective real-world study, patients with inflammatory diseases treated with RP were switched to CT-P13 (n = 7) or continued on RP (n =...

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The expression of ribosomal protein (RP) genes requires a substantial part of cellular transcription, processing and translation resources. Thus, the RP expression must be tightly regulated in response to conditions that compromise cell survival. In Saccharomyces cerevisiae cells, regulation of the RP gene expression at the transcriptional, mature mRNA stability and translational levels during ...

PURPOSE Predictive factors for radiation pneumonitis (RP) after helical tomotherapy (HT) may differ from those after linac-based radiotherapy. In this study, we identified predictive factors for RP in patients with lung cancer treated with HT. MATERIALS AND METHODS We retrospectively analyzed clinical, treatment-related and dosimetric factors from 31 patients with lung cancer treated with HT....

We evaluated associations of interstitial changes with radiation pneumonitis (RP) for patients treated with thoracic radiotherapy. Between 2005 and 2009, patients who received thoracic radiotherapy of 40 Gy or more for lung cancer or thymic tumors and were followed-up for more than 6 months were eligible for this study. Possible risk factors for RP included the presence of interstitial changes ...

Immunologically based studies of host-tumor interactions have gained popularity in head and neck oncology and histopathological determination of lymph node reactivity has been shown to correlate with survival. However, little is known about lymph node reaction patterns in the "normal" neck. In a prospective histomorphologic study 1,024 cervical lymph nodes (CLN) were dissected at autopsy from 2...

PURPOSE To study the association between retinitis pigmentosa (RP) and the progression of diabetic retinopathy (DR). METHODS Using the Longitudinal Health Insurance Database 2000 of Taiwan, we identified individuals with an initial diagnosis for RP during the period of 1997-2008. A non-RP comparison group, 10-fold frequency matched by sex, age, index year and the year of diabetes diagnosed, w...

to identify mental disorders and their prevalence in patients with retinitis pigmentosa (rp).this descriptive study was carried out between january 2009 and january 2010 on 417 patients with rp, who were members of iran rp center. the necessary data were collected using questionnaires consisting two parts: the background characteristics and questions assessing the mental health and screening pe...

a b s t r a c t introduction: diabetes mellitus is accompanied with disturbances in learning, memory, and cognitive skills in the human society and experimental animals. due to anti-diabetic and antioxidant activity of rumex patientia (rp), this research study was conducted to evaluate the efficacy of chronic rumex patientia feeding on alleviation of learning and memory disturbance in streptozo...

Improving solubility of rock phosphate is critical for phosphorus (P) management in cropping. This experiment was conducted during 2010 to determine the P solubilized from rock phosphate (RP) through composting with fresh poultry litter (PL). The RP used in the experiment was collected from Hazara area of Khyber Pakhtunkhwa (KP) province, Pakistan. The treatments comprised of PL alone, PL+RP, a...