PURPOSE This study examined the reliability and validity of a Falls Risk Assessment (FRA) tool developed to identify risk factors associated with falls in homebound older adults. DESIGN AND METHODS FRA scores of 307 Medicare-eligible adults over 65 admitted sequentially to a home health agency (HHA) were analyzed retrospectively using a case-control design. A total of 18 subjects participated...

OBJECTIVE To establish the allelic and genotypic frequencies related to apolipoprotein E (ApoE) polymorphism and association of the genotypes with risk factors and cardiovascular morbidity in an elderly population with longevity. METHODS We analyzed 70 elderly patients aged 80 years or more who were part of the Projeto Veranópolis. We used the gene amplification technique through the polymera...

The S subunits of type I DNA restriction/modification enzymes are responsible for recognising the DNA target sequence for the enzyme. They contain two domains of approximately 150 amino acids, each of which is responsible for recognising one half of the bipartite asymmetric target. In the absence of any known tertiary structure for type I enzymes or recognisable DNA recognition motifs in the hi...

The cytosolic phosphenolpyruvate carboxykinase [PEPCK; GTP:oxaloacetate carboxy-lyase (transphosphorylating), EC 4.1.1.32] gene was isolated from a rat genomic library, and a map of the methylatable sites C-C-G-G and G-C-G-C has been constructed. The extent of methylation of 18 sites in the PEPCK gene in adult liver, kidney, spleen, and heart muscle and in fetal liver has been analyzed using th...

Gedurende die afgelope paar jaar het interessante tendense in arbeidsregtelike verband neerslag gevind – wat aan een kant deur regspragmatisme gekenmerk word en te verwelkom is, maar ander kant, 'n stremmende bekommernis oor onnodige dualisme voorgaande neutraliseer. Die Suid-Afrikaanse arbeidsverhoudinge-dinamika is verteenwoordigend van “regswoelinge” aantal jare hierdie aktuele terrein vandi...

Lymphatic filariasis caused by Brugia malayi is highly prevalent in Narathiwat province of Thailand. The World Health Organization has aimed to eliminate the disease globally by the year 2020. To achieve the goal, assessment of the real disease situation should be integrated as part of the control program. The preliminary data for long-term study of the disease situation in this endemic area is...

BACKGROUND Several studies hinted about the clustering of risk variables of the metabolic syndrome (MS) and suggested that the underlying genetic polymorphisms could be responsible for the increasing incidence of coronary heart disease (CHD) in people of Indian origin. Therefore, identification of the components of the MS along with the genetic factors could be one of the aspects to make an att...

Background: The hemi-hamate arthroplasty (HHA) can restore joint congruity and stability in chronic fracturedislocationsof the proximal interphalangeal joint (PIPJ). Purpose of this study was to compare the width of the distalhamate articular surface (DHAS) to the width of the base of the middle phalanges (P2) of the fingers. We hypothesizedthe dimensions of the width of the D...

BACKGROUND Broadly cross-reactive, neutralizing human monoclonal antibodies, including 2F5, 2G12, 4E10 and IgG1 b12, can inhibit HIV-1 infection in vitro at very low concentrations. We examined the ability of these antibodies to inhibit cell-cell fusion between Clone69TRevEnv cells induced to express the viral envelope proteins, gp120/gp41 (Env), and highly CD4-positive SupT1 cells. The cells w...