The title compound, C(17)H(20)N(2)O(6), belongs to the monastrol-type of anti-cancer agents and was selected for crystal structure determination in order to confirm its mol-ecular structure and explore some aspects of its structure-activity relationships. The central tetra-hydro-pyrimidine ring has a flat-envelope conformation. The 4-hydroxy-phenyl group occupies a pseudo-axial position and is ...

The crystal structure of the title compound, C(16)H(11)F(3)N(4)O(2)S, is stabilized in the form of polymeric chains by N-H⋯O inter-actions. In the mol-ecular structure, two S(5) ring motifs are formed by intra-molecular N-H⋯N and N-H⋯O hydrogen bonding and two S(6) rings are present due to N-H⋯O and C-H⋯S inter-actions. π-π inter-actions are present with distances of 3.2735 (17), 3.563 (2) and ...

In the crystal structure of the title compound, C(43)H(46)NO(13)·0.5H(2)O, the mol-ecule assumes a U-shaped conformation, the terminal benzene rings being approximately parallel and partially overlapped with each other. The mol-ecule contains eight alicyclic and heterocyclic rings. The cyclo-hexane rings adopt chair conformations, the other three six-membered carbocyclic rings form a bicyclo-[2...

In the title compound, C(22)H(21)N(3)O(6)Se, the heterocyclic ring makes dihedral angles of 50.03 (11) and 67.75 (11)°, respectively, with the benzene and phenyl rings. The terminal C atoms of the ester groups are disordered over two positions: the site occupancies for the C atoms are 0.62 (3)/0.38 (3) and 0.48 (3)/0.52 (3). In the crystal structure, weak intra- and inter-molecular C-H⋯O inter-...

There are two independent mol-ecules in the the asymmetric unit of the title compound, C(11)H(14)N(2)O. The heterocyclic ring of the bicyclic system has a sofa conformation, with the C atom bearing the two methyl groups displaced by 0.541 (7) Å from the rest of the atoms of the ring [planar to within 0.064 (9) Å]. Mol-ecules are linked into centrosymmetric dimers via N-H⋯O hydrogen bonds.

The monomeric title compound, C(9)H(6)BrCl(2)NO(3)S, has an envelope-shaped thia-zine ring with the S atom 0.879 (9) Å out of the mean square plane of the envelope. The π-π distances between the centroids of the heterocyclic rings are 4.191 (5) and 4.110 (5) Å. The closest intermolecular inter-actions between the O atoms of the carbonyl and sulfonyl groups with Br and Cl atoms are 2.987 (7) and...

In the mol-ecule of the title compound, C(38)H(37)N(3)O(7), the pyrrolidine ring adopts a twist conformation and the six-membered heterocyclic ring has a boat conformation. In the crystal structure, mol-ecules are linked into a three-dimensional framework through inter-molecular C-H⋯O hydrogen bonds. One ethyl group is disordered over two positions with occupancies 0.67 (2)/0.33 (2).

The title compound, C(18)H(20)N(2)O(2), was prepared by Mannich-type reaction of phenol, ethane-1,2-diamine and formaldehyde. The heterocyclic rings adopt half-chair conformations. The acyclic methyl-ene groups attached to the N atoms are in an axial position. In the crystal, weak C-H⋯O hydrogen bonds link the mol-ecules into dimers. These dimers are further connected via C-H⋯π contacts.

The heterocyclic ring of the title compound, C9H7BrO2, obtained by bromination of 4-chromanone with copper bromide, adopts a half-chair conformation. The supramol-ecular structure is governed by a weak C-H⋯O hydrogen bond. There is also π-π stacking between symmetry-related benzene rings; the centroid-centroid distance is 3.9464 (18), the perpendicular distance between the rings is 3.4703 (11) ...

The title compound, C(10)H(13)NO, was obtained as the unexpected, almost exclusive, product in the attempted synthesis of a manganese(I)-N-heterocyclic carbene (NHC) complex. The dihedral angle between the planes of the formamide moiety and the aryl ring is 68.06 (10)°. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds, forming infinite chains along the c axis.