نتایج جستجو برای: heterocycles

تعداد نتایج: 2986  

Journal: :New Journal of Chemistry 2023

Correction for ‘Recent developments in the solvent-free synthesis of heterocycles’ by Nilabrata Dey et al. , New J. Chem. 2023, https://doi.org/10.1039/d3nj01991h.

Journal: :Chemical Communications 2021

A photochemical ring expansion of 6- to 8-membered nitrogen heterocycles can be combined with a thermal aminocyclobutenones give efficient access azocines and benzoazocines.

Journal: :Chemical reviews 2014
Benjamin H Rotstein Serge Zaretsky Vishal Rai Andrei K Yudin

Benjamin H. Rotstein,†,‡ Serge Zaretsky,† Vishal Rai,†,§ and Andrei K. Yudin*,† †Davenport Research Laboratories, Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario Canada, M5S 3H6 ‡Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, and Department of Radiology, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 021...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2008
Christopher T Walsh Elizabeth M Nolan

M icrobes employ several catalytic strategies to transform conformationally f lexible peptide chains into rigidified scaffolds that possess antibiotic or toxin activity. Prominent examples include the biosynthesis of the -lactam antibiotics of the penicillin and cephalosporin families (1) and the maturation of vancomycin (2) where distinct structural modifications to the nascent peptide chains ...

Journal: :The Journal of Organic Chemistry 2014

Journal: :European Journal of Organic Chemistry 2021

Nitroenynes are an interesting electrophile in asymmetric organocatalysis, due to the versatility of functional groups present its structure. This review covers organocatalytic examples using this and application for synthesis chiral heterocycles.

Journal: :CrystEngComm 2022

Fused azolate ligands are hydrolytically-stable linkers for metal–organic frameworks. Their unique geometries and capacity functionalisation have opened new pathways at the convergence of simple N-heterocycles biologically relevant purines.

Journal: :Bioorganic & medicinal chemistry 2012
Muthu K Kathiravan Amol B Salake Aparna S Chothe Prashik B Dudhe Rahul P Watode Maheshwar S Mukta Sandeep Gadhwe

In recent years their has been an increased use of antifungal agents and has resulted in the development of resistance to drugs. Currently, use of standard antifungal therapies can be limited because of toxicity, low efficacy rates. Different types of mechanisms contribute to the development of resistance to antifungals. This has given raise to search for a new heterocycle with distinct action ...

Journal: :Chimia 2011
Davinia Fernández González Filippo De Simone Jonathan P Brand Stefano Nicolai Jérôme Waser

One of the major challenges faced by organic chemistry is the efficient synthesis of increasingly complex molecules. Since October 2007, the Laboratory of Catalysis and Organic Synthesis (LCSO) at EPFL has been working on the development of catalytic reactions based on the Umpolung of the innate reactivity of functional groups. Electrophilic acetylene synthons have been developed using the exce...

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