INTRODUCTION Nerve growth factor (NGF) has an important role in the generation of discogenic pain. We hypothesized that annular rupture is a trigger for discogenic pain through the action of NGF. In this study, the protein levels of NGF in discs from patients with disc herniation were examined and compared with those from discs of patients with other lumbar degenerative disc diseases. METHODS...

OBJECTIVE To describe the use of intermittent cervical traction in managing 4 patients with cervical radiculopathy and large-volume herniated disks. CLINICAL FEATURES Four patients had neck pain radiating to the arm. The clinical examination was typical in all cases for radiculopathy of cervical origin. Magnetic resonance imaging (MRI) of the cervical spine revealed large-volume herniated dis...

A 53-year-old man had had pain for 2 months in the left lower extremity radiating to the thigh . The pain had begun suddenly after he had lifted a heavy object. Clinical examination showed mildly decreased strength in the left leg, normal reflexes, and decreased sensation to pinprick in the left L3 nerve root distribution. A herniated disk at the L3 level was suspected, and myelography and CT o...

Forty canine patients with a presumptive diagnosis of the intervertebral disc herniation at the thoracolumbar region were imaged. A neurological examination was performed and all patients were classified under four grades by the examination. The degrees of attenuation of the herniated disc material were measured in Housefield units (HU) in each image. The ratio of the area to herniated disc mat...

A 25-year-old man had several episodes of low back pain over a 3-year period. The initial episodes were described as simple backaches, unassociated with radicular pain, and were relieved by bed rest and aspirin . One year later, the patient sought chiropractic therapy on two occasions for recurrent backache. He failed to obtain relief and, while under treatment, began to experience radiating pa...

BACKGROUND The purpose of this study was to assess the correlation between the 2-dimensional (2D) extent of orbital defects and the 3-dimensional (3D) volume of herniated orbital content in patients with an orbital wall fracture. METHODS This retrospective study was based on the medical records and radiologic data of 60 patients from January 2014 to June 2016 for a unilateral isolated orbital...

BACKGROUND Abnormal intervertebral movements of spine have been reported to be associated with trauma and pathological conditions. The importance of objective spinal motion imaging assessment in the frontal plane was frequently underestimated. The clinical evaluation of the segmental motion contribution could be useful for detecting the motion pattern of individual vertebrae. Therefore the purp...

results the depression and disability scores of patients before lumbar discectomy significantly decreased after surgery. conclusions our results indicate that lumbar discectomy surgery significantly improved depression and disability in patients with chronic herniated discs. patients and methods one hundred forty-eight patients with chronic low back pain and radicular leg pain were included in ...