نتایج جستجو برای: heritability
تعداد نتایج: 10805 فیلتر نتایج به سال:
BACKGROUND Leucocyte telomere length (LTL) is a complex trait associated with ageing and longevity. LTL dynamics are defined by LTL and its age-dependent attrition. Strong, but indirect evidence suggests that LTL at birth and its attrition during childhood largely explains interindividual LTL variation among adults. A number of studies have estimated the heritability of LTL, but none has assess...
BACKGROUND Studies of related individuals have consistently demonstrated notable familial aggregation of cancer. We aim to estimate the heritability and genetic correlation attributable to the additive effects of common single-nucleotide polymorphisms (SNPs) for cancer at 13 anatomical sites. METHODS Between 2007 and 2014, the US National Cancer Institute has generated data from genome-wide a...
Heritability estimates for specific language impairment (SLI) have been inconsistent. Four twin studies reported heritability of 0.5 or more, but a recent report from the Twins Early Development Study found negligible genetic influence in 4-year-olds. We considered whether the method of ascertainment influenced results and found substantially higher heritability if SLI was defined in terms of r...
Human height variation is determined by genetic and environmental factors, but it remains unclear whether their influences differ across birth-year cohorts. We conducted an individual-based pooled analysis of 40 twin cohorts including 143,390 complete twin pairs born 1886-1994. Although genetic variance showed a generally increasing trend across the birth-year cohorts, heritability estimates (0...
CONTEXT In contrast to the large number of studies in children, there is little information on the contribution of genetic factors to Attention Deficit Hyperactivity Disorder (ADHD) in adults. OBJECTIVE To estimate the heritability of ADHD in adults as assessed by the ADHD index scored from the CAARS (Conners' Adult ADHD Rating Scales). DESIGN Phenotype data from over 12,000 adults (twins, ...
Variation in the hematocrit of a passerine bird across life stages is mainly of environmental origin
The heritability of the hematocrit in adult, breeding pied flycatchers Ficedula hypoleuca is examined in a southern European population across seven years to see the consistency, or lack thereof, of patterns found with the trait at fledgling age where no significant heritability could be detected. While the across-years repeatability of the trait in adult, breeding birds was low but significant...
The concept of the mutation component of a genetic trait is discussed and its relation to heritability investigated. It is found that for qualitative traits held in the population by opposing directional selection and mutation, the mutation component equals the broad sense heritability. The mutational component of a quantitative trait with an intermediate optimum is found generally to be betwee...
Cheverud and Buikstra (1981) demonstrated a tendency for nonmetric traits representing the number of foramina to have lower heritabilities than those representing hyperstotic or hypostotic traits in a sample of rhesus macaques. Based on this observation, Cheverud and Buikstra hypothesize that differences in the heritability of the two sets of traits may be due to differences in trait etiology. ...
OBJECTIVE To estimate the familiality and heritability of binge eating disorder (BED). METHOD We used a new ACE structural equation model to estimate heritability from a case-control family study of BED conducted in the Boston area. The sample consisted of 150 overweight/obese probands with lifetime BED by DSM-IV criteria, 150 overweight/obese probands without lifetime BED, and 888 of their f...
Estimation of the limits of heritability of traits by comparison of monozygotic and dizygotic twins.
This paper has three aims: (1) to present a new formula for extracting heritability estimates from twin data; (2) to show the results of the application of the formula to data from past studies of the heritability of intelligence, scholastic achievement, personality traits, and physical characteristics; and (3) to urge that heritability estimates be obtained in all large-scale educational testi...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید