نتایج جستجو برای: hereditary nephritis

تعداد نتایج: 94751  

Journal: :Annals of the rheumatic diseases 1987
H Gur Y Kopolovic D J Gross

Predominant interstitial nephritis is a rare manifestation of systemic lupus erythematosus. Only seven cases have been reported in the literature. Owing to the rarity of this entity, the natural history of predominant interstitial nephritis in lupus has not been adequately recorded and an appropriate therapeutic approach has yet to be defined. In this report we present the case of a 25 year old...

Journal: :Seminars in nephrology 2007
Mary Anne Dooley Ronald J Falk

Improved patient survival after treatment of lupus nephritis with corticosteroids, immunosuppressants, and renal replacement therapy allows greater emphasis on long-term management issues. In particular, the recent focus has been on therapies to treat nephritis with fewer adverse effects compared with cyclophosphamide and immunosuppressive regimens. Issues complicating clinical trial design in ...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011
Cornelia Bigler Helmut Hopfer Doris Danner Monica Schaller Michael J Mihatsch Marten Trendelenburg

BACKGROUND In systemic lupus erythematosus patients, a strong association between the occurrence of antibodies against complement C1q (anti-C1q) and lupus nephritis can be observed. However, the predictive value of anti-C1q titres for a renal flare remains to be determined. Increasing titres of anti-C1q before the occurrence of clinical apparent nephritis might not only serve as a clinical para...

Journal: :Clinical journal of the American Society of Nephrology : CJASN 2010
Andrew Smyth Guilherme H M Oliveira Brian D Lahr Kent R Bailey Suzanne M Norby Vesna D Garovic

BACKGROUND AND OBJECTIVES Studies of the impact of systemic lupus erythematosus (SLE) and its pregnancy complications have yielded conflicting results. Major limitations of these studies relate to their small numbers of patients and retrospective designs. The aim of this study was to perform a systematic literature review of pregnancy outcomes in women with SLE and a meta-analysis of the associ...

Journal: :The Journal of Experimental Medicine 1939
G. H. Whipple F. S. Robscheit-Robbins

Spontaneous glomerulonephritis develops not infrequently (11 per cent incidence) in the anemia colony. The course of the nephritis is insidious and usually extends over several years but ends in uremia, often with terminal bronchopneumonia. Hemoglobin production in these standard anemic dogs is well established as related to various standard food factors. These tests are summarized in the table...

2012
Antonio De Pascalis Erasmo Buongiorno

Acute interstitial nephritis is a relevant cause of acute renal failure. Drugs are the predominant cause, followed by infections and idiopathic lesions. Acute interstitial nephritis as a form of hypersensitivity reaction is an uncommon manifestation in the setting of human parasitic infections. We present a case of acute interstitial nephritis in association with Giardia infection in a 54-year-...

2015
Clio P. Mavragani George E. Fragoulis George Somarakis Alexandros Drosos Athanasios G. Tzioufas Haralampos M. Moutsopoulos Carlos Antonio Guillen Astete.

The authors aimed to explore whether distinct clinical, serological, and urinalysis findings are associated with specific histological classes of lupus nephritis. Clinical and laboratory features were recorded at the time of clinical diagnosis from 297 consecutive patients with biopsy-confirmed lupus nephritis. Univariate and logistic regression analyses were performed and a risk score was deve...

Journal: :Internal medicine 1994
H Makino Y Hayashi Y Yamasaki K Shikata N Kashihara S Kira Z Ota

The significance of necrosis (karyorrhexis), among the most characteristic findings in lupus nephritis, was evaluated by studying the correlation between the existence of necrosis in renal biopsy specimens and laboratory findings. The subjects were 54 patients with diffuse proliferative lupus nephritis and 6 patients with focal proliferative lupus nephritis selected from 143 patients with lupus...

Journal: :Clinical journal of the American Society of Nephrology : CJASN 2009
Catherine Melander Marion Sallée Pierre Trolliet Sophie Candon Xavier Belenfant Eric Daugas Phillipe Rémy Virginie Zarrouk Evangéline Pillebout Christian Jacquot Jean-Jacques Boffa Alexandre Karras Virginie Masse Philippe Lesavre Caroline Elie Isabelle Brocheriou Bertrand Knebelmann Laure-Hélène Noël Fadi Fakhouri

BACKGROUND AND OBJECTIVES Standard treatment for lupus nephritis, including corticosteroids and cyclophosphamide, is efficient but is still associated with refractory or relapsing disease, or severe deleterious effects. Rituximab, a monoclonal chimeric anti-B cell antibody, is increasingly used in patients with lupus nephritis, but reported series were small and had a short follow-up. DESIGN,...

Journal: :Clinical science and molecular medicine 1975
W F Clark M L Lewis J S Cameron V Parsons

1. Platelet survival and an index of the localization of platelets in the kidney were studied in patients with the proliferative nephritis of systemic lupus erythematosus, either focal or diffuse, and in control subjects. Platelet survival was reduced in patients with proliferative lupus nephritis, more in those with diffuse rather than focal renal involvement. 2. The index of renal platelet lo...

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