BACKGROUND AND PURPOSE Low serum concentrations of the amino acid homoarginine have been associated with endothelial dysfunction and an increased risk of all-cause and cardiovascular mortality. We aimed to investigate whether homoarginine levels are also associated with fatal strokes and a history of nonfatal cerebrovascular disease. METHODS Serum homoarginine was measured in 3305 participant...

BACKGROUND AND PURPOSE Outdoor air pollution represents a potentially modifiable risk factor for stroke. We examined the link between ambient pollution and mortality up to 5 years poststroke, especially for pollutants associated with vehicle exhaust. METHODS Data from the South London Stroke Register, a population-based register covering an urban, multiethnic population, were used. Hazard rat...

The posterior circulation is part of the brain circulation that is subject to stroke. Strokes which involve the posterior circulation account for approximately 25% of all ischemic strokes, and about 10-20% of all hemorrhagic strokes. While the mortality rate from ischemic strokes in posterior circulation could be as low as 4%, the cerebellar and pontine hemorrhages carry a mortality rate close ...

BACKGROUND Childhood primary angiitis of central nervous system (cPACNS) is rare idiopathic vasculitis most frequently in adults. Children with this disorder can present with a range of neurological symptoms and signs including decreased consciousness, seizures, hemiparesis, cranial nerve deficits, and cognitive deficits. Delayed diagnosis and treatment may compromise the outcome. Therapeutic m...

It is well known that atrial fibrillation (AF) is the most frequent sustained cardiac rhythm disturbance, occurring in between 1 and 2% of the general population. AF confers a fivefold risk of stroke and one in five of all strokes plus an unknown number of “cryptogenic strokes” is attributable to AF. (1) The mean incidence of a disabling stroke in AF patients is 2.5%/ year, which increase to 7%...

Elevated blood pressure (BP) demonstrates a consistent, strong, and graded relationship across the entire spectrum at levels 110 mm Hg systolic with several cardiovascular disease outcomes including cardiovascular death, myocardial infarction (MI), stroke, heart failure, and renal dysfunction.1 The population attributable risk due to elevated BP is large and consistent in all ethnic groups and ...

Stroke is a disease of the brain functional disorders that arises suddenly and lasts more than 24 hours or ends in death situation without known cause other vascular disorders. Strokes are generally classified into ischemic stroke (non-hemorrhagic) hemorrhagic stroke, One risk factors dyslipidemia. The aim this study was to describe dyslipidemia acute patients at Arifin Achmad Regioal General H...

BACKGROUND AND PURPOSE Stroke is a common and serious clinical manifestation of Fabry disease, an X-linked lysosomal storage disorder caused by deficiency of alpha-galactosidase A activity. This study was undertaken to better understand the natural history of cerebrovascular manifestations of Fabry disease. METHODS Data from 2446 patients in the Fabry Registry were analyzed to identify clinic...

BACKGROUND AND PURPOSE Cholesterol levels are inconsistently associated with the risk of hemorrhagic stroke. The purpose of this study is to assess their relationships using a meta-analytic approach. METHODS We searched PubMed and Embase for pertinent articles published in English. Only prospective studies that reported effect estimates with 95% confidential intervals (CIs) of hemorrhagic str...

CONTEXT The effect of fish consumption or long-chain omega-3 polyunsaturated fatty acid (PUFA) intake on risk of stroke remains uncertain. OBJECTIVE To examine the relation of fish consumption and long-chain omega-3 PUFA intake and risk of stroke in men. DESIGN AND SETTING The Health Professional Follow-up Study, a US prospective cohort study with 12 years of follow-up. PARTICIPANTS A tot...