BACKGROUND Pregnant women with a mechanical heart valve (MHV) are at a heightened risk of a thrombotic event, and their absolute need for adequate anticoagulation puts them at considerable risk of bleeding and, with some anticoagulants, fetotoxicity. METHODS AND RESULTS Within the prospective, observational, contemporary, worldwide Registry of Pregnancy and Cardiac disease (ROPAC), we describ...

Prosthetic heart valve (PHV) replacement replaces a heart disease with another one. There is no ideal prosthetic heart valve. All of the prosthetic heart valves need to be followed by caution. PHV diseases (PHVD) includes a group of pathologic processes like prosthetic valve obstruction, thromboembolism and regurgitation. Correct diagnosis and treatment of these pathologic situations will decre...

Heart valve replacement represents the most common surgical therapy for end-stage valvular heart diseases. A major drawback that all contemporary heart valve replacements have in common is the lack of growth, repair and remodelling capability. In order to overcome these limitations, the emerging new field of tissue engineering is focusing on the in vitro generation of functional, living heart v...

The delicate leaflets that make up vertebrate heart valves are essential for our moment-to-moment existence. Abnormalities of valve formation are the most common serious human congenital defect. Despite their importance, relatively little is known about valve development. We show that the initiation of heart valve morphogenesis in mice requires calcineurin/NFAT to repress VEGF expression in the...

BACKGROUND The CardioMEMS Heart Failure System is a well validated tool to optimize management of systolic and diastolic heart failure and has been shown to reduce the risk of hospitalization by 37%. We are reporting a unique case of acute aortic valve insufficiency as a first sign of endocarditis, detected early in a patient with the CardioMEMS device. CASE REPORT A 79-year-old man with dual b...

patients and methods ninety-eight children with congenital ps referred to affiliated hospital of jining medical college were recruited from october 2013 to march 2015. participants were divided into four groups according to different ages (0 - 1, 1 - 3, 3 - 7, 7 - 14), or three groups according to different heart rates (< 90, 90 - 110, > 110). image quality of pulmonary valves was assessed base...

Abstract The American College of Cardiology/American Heart Association practice guidelines suggest bioprosthetic aortic and mitral valve replacement is a reasonable option for patients older than 65 years selected younger according to patients’ preference. However, routine use valves in remains controversial. Patients prevalence avoid anticoagulation, decreasing operative risks reoperations, th...

Calcific aortic valve disease is the most common and life threatening form of valvular heart disease, characterized by stenosis and regurgitation, which is currently treated at the symptomatic end-stages via open-heart surgical replacement of the diseased valve with, typically, either a xenograft tissue valve or a pyrolytic carbon mechanical heart valve. These options offer the clinician a choi...

Assessment of Machine Learning Approaches to Predict in-Hospital Mortality in Patients Underwent Prosthetic Heart Valve Replacement Surgery

Seven cases of single ventricle, six cases of hypoplasia of the right heart (tricuspid atresia), and one case of hypoplasia of the left heart were investigated with reflected ultrasound. In hypoplasia of the right heart there was abnormal anterior movement of the mitral valve; in hypoplasia of the left heart, abnormal anterior movement of the tricuspid valve, and in single ventricle, similiar m...