CASE This is a 27-year-old man with migraines without aura for about 15 years that have increased in frequency to about twice a week in the last 1 year. The headaches are relieved within 1 hour by a triptan. Neurological examination was normal. Family history reveals that both parents, his brother, and sister are all migraineurs.A magnetic resonance imaging (MRI) of the brain obtained at the pa...

Any patient suffering from a headache sufficiently severe to cause our advice to be sought should be thoroughly examined. Such a case will amply repay careful investigation. Simply to order a sedative is not a credit to the highest conception of modern medicine. In most cases, gastro-intestinal or gynaecological disorders, errors of refraction and septic foci, especially teeth, will not be over...

Primary headaches such as migraine and cluster headache are neurovascular disorders. Migraine is a painful, incapacitating disease that affects a large portion of the adult population with a substantial economic burden on society. The disorder is characterised by recurrent unilateral headaches, usually accompanied by nausea, vomiting, photophobia and/or phonophobia. A number of hypothesis have ...

Thunderclap headache, a severe headache which is maximal in intensity at onset, is associated with numerous underlying disorders, including subarachnoid hemorrhage, unruptured intracranial aneurysm, cervical artery dissection, cerebral venous sinus thrombosis, stroke, intracranial hemorrhage, reversible cerebral vasoconstriction syndrome, and reversible posterior leukoencephalopathy. After excl...

CASE HISTORY This 50-year-old white man has a 5-year history of headaches described as an 8/10 in intensity stabbing in the left temple and sometimes around the left ear associated with tearing and redness of the left eye, congestion of the left nares, and light and noise sensitivity but no aura. During a headache, he prefers to sit or lie down. Without treatment, the headache lasts about 2 hou...