BACKGROUND Interest in developing physically active pediculicides has identified new active substances. The objective was to evaluate a new treatment for clinical efficacy. METHODS AND FINDINGS We describe the selection of 1,2-octanediol as a potential pediculicide. Clinical studies were community based. The main outcome measure was no live lice, after two treatments, with follow up visits ov...

Blood-sucking lice of humans have extensively fragmented mitochondrial (mt) genomes. Human head louse and body louse have their 37 mt genes on 20 minichromosomes. In human pubic louse, the 34 mt genes known are on 14 minichromosomes. To understand the process of mt genome fragmentation in the blood-sucking lice of mammals, we sequenced the mt genomes of the domestic pig louse, Haematopinus suis...

Pediculus humanus capitis, the head louse, is an obligate blood-sucking ectoparasite that occurs in six divergent mitochondrial clades (A, D, B, F, C and E). Several studies reported presence of different pathogenic agents lice specimens collected worldwide. These findings suggest louse could be a dangerous vector serious public health problem. Herein, we aimed to study genetic diversity, PHUM5...

Received: December 2011, Accepted: September 2012 Background: Head lice infestation is one of the most common parasitic infections with a long history in the world. The purpose of this study was to determine the prevalence of head lice infestation among 3-6 years old children going to nursery schools in Kashan, Iran in 2009. Materials and Methods: This cross-sectional study was performed on 120...

Relapsing fever, caused by spirochaetes belonging to the genus Borrelia, was once the cause of worldwide epidemic disease. This was largely through infection with the louse-borne form of the disease, caused by Borrelia recurrentis (louse-borne relapsing fever (LBRF)). During the last century, we have witnessed the demise of this infection, largely owing to improved standards of living and the i...

For some salmon populations, the individual and population effects of sea lice (Lepeophtheirus salmonis) transmission from sea cage salmon farms is probably mediated by predation, which is a primary natural source of mortality of juvenile salmon. We examined how sea lice infestation affects predation risk and mortality of juvenile pink (Oncorhynchus gorbuscha) and chum (O. keta) salmon, and dev...

This is a survey of 120 children for scabies and head lice infestations in a welfare home in Pulau Pinang. Children from this welfare home (Rumah Kanak-Kanak Taman Bakti, Kepala Batas, Pulau Pinang) were randomly selected. Majority of them were Malays (72.5%) and the rest were Indians. The infestation rates were highest in the 10-12 years age group with 46% and 70% for scabies and head lice res...

The first mycetome was discovered more than 340 yr ago in the human louse. Despite the remarkable biology and medical and social importance of human lice, its primary endosymbiont has eluded identification and characterization. Here, we report the host-symbiont interaction of the mycetomic bacterium of the head louse Pediculus humanus capitis and the body louse P. h. humanus. The endosymbiont r...

Pediculosis capitis is a common disease in industrialized countries, but there are also areas in sub-Saharan Africa where head lice infestations are highly endemic. However, there are no data available from the African continent on the accuracy of head lice diagnosis made by affected individuals. We performed a door-to-door survey in Skanko village (Kwara State, Central Nigeria). Individuals we...