Recently, it has been published that cerium (Ce) oxide nanoparticles (CNP; nanoceria) are able to downregulate tumor invasion in cancer cell lines. Redox-active CNP exhibit both selective pro-oxidative and antioxidative properties, the first being responsible for impairment of tumor growth and invasion. A non-toxic and even protective effect of CNP in human dermal fibroblasts (HDF) has already ...

We consider a general online scheduling problem on a single machine with the objective of minimizing ∑ j wjg(Fj), where wj is the weight/importance of job Jj , Fj is the flow time of the job in the schedule, and g is an arbitrary non-decreasing cost function. Numerous natural scheduling objectives are special cases of this general objective. We show that the scheduling algorithm Highest Density...

Lamins A/C have been implicated in DNA damage response pathways. We show that the DNA repair protein 53BP1 is a lamin A/C binding protein. In undamaged human dermal fibroblasts (HDF), 53BP1 is a nucleoskeleton protein. 53BP1 binds to lamins A/C via its Tudor domain, and this is abrogated by DNA damage. Lamins A/C regulate 53BP1 levels and consequently lamin A/C-null HDF display a 53BP1 null-lik...

Spectra of 115 HDF galaxies to I 25 mag were obtained by the Santa Cruz DEEP group with the Keck LRIS multislit spectrograph and combined with detailed structural measurements from the HDF images to (i) derive evolution for a sample of disk galaxies at z 0:5 using the Tully-Fisher relation, (ii) characterize, from size and velocity width data, the global properties to z 1 of a sample of 60 \com...

We report a 2.1 μm band mode-locked holmium-doped fiber (HDF) laser with tunable wavelength and pulse width in dissipative soliton resonance (DSR) region for the first time to our knowledge. A piece of HDF is pumped by home-made 1.9 source, nonlinear-amplifying-loop-mirror structure used realize mode-locking operation net anomalous dispersion. The repetition rate 8.97 MHz. duration can be adjus...

We report the discovery of a variable object in the Hubble Deep Field North (HDF-N) which has brightened, during the 8.5 days sampled by the data, by more than 0.9 mag in I814 and about 0.7 mag in V606, remaining stable in B450. Subsequent observations of the HDF-N show that two years later this object has dimmed back to about its original brightness in I814. The colors of this object, its brig...

Solar active regions (ARs) play a fundamental role in driving many of the geo-effective eruptions which propagate into System. However, we are still unable to consistently predict where and when ARs will occur across solar disk by identifying pre-emergence signatures observables such as Doppler velocity (without using Helioseismic methods). Here aim determine earliest time at signatures, specif...

IntroductionHigh convection volumes in haemodiafiltration (HDF) result improved survival, however, it remains unclear whether is achievable all patients.MethodsCONVINCE, a randomised controlled trial, patients with end-stage kidney disease 1:1 to high-dose HDF versus high-flux haemodialysis continuation. We evaluated the proportion of achieving target: volume per visit ≥23 L (range ±1 L), at ba...