Enhancins are metalloproteinases, first identified in granuloviruses, that can enhance nucleopolyhedrovirus (NPV) potency. We had previously identified two enhancin genes (E1 and E2) in the Lymantria dispar multinucleocapsid NPV (LdMNPV) and showed that both were functional. For this study, we have extended our analysis of LdMNPV enhancin genes through an immunocytochemical analysis of E1 and E...

background wound healing is a dynamic process with inflammatory response and oxidative reaction in the damaged area. alpha ointment (ao) and arnebia euchroma (arnebia) are herbal medicines with antioxidant and anti-inflammatory effects that can be used as wound healing agents. ao is a commonly used ointment while arnebia is a newly introduced one. objectives we aimed to compare the effects of a...

Replication of the genome of human papillomaviruses (HPV) is initiated by the recruitment of the viral E1 helicase to the origin of DNA replication by the viral E2 protein, which binds specifically to the origin. We determined, for HPV type 11 (HPV-11), that the C-terminal 296 amino acids of E1 are sufficient for interaction with the transactivation domain of E2 in the yeast two-hybrid system a...

Papillomaviruses establish a long-term latency in vivo by maintaining their genomes as nuclear plasmids in proliferating cells. Bovine papillomavirus type 1 encodes two proteins required for viral DNA replication: the helicase E1 and the positive regulator E2. The homodimeric E2 is known to cooperatively bind to DNA with E1 to form a preinitiation complex at the origin of DNA replication. The v...

Let E1 and E2 be elliptic curves in Legendre form with integer parameters. We show there exists a constant C such that for almost all primes, but at most pairs of points on the reduction E1×E2 modulo p having equal x coordinate, least one among P1 P2 has large group order. also similar abundance over finite fields elements whose images under set rational functions have multiplicative orders.

We have previously reported the production of hepatitis C virus-like particles (HCV-LP) using a recombinant baculovirus containing the cDNA of the HCV structural proteins (core, E1, and E2). These particles resemble the putative HCV virions and are capable of inducing strong and broad humoral and cellular immune responses in mice. Here we present evidence on the immunogenicity of HCV-LP and the...

Hepatitis C virus (HCV) is a major cause of posttransfusion and community-acquired hepatitis, and a majority of individuals infected with this virus will subsequently develop chronic hepatitis. Characterization of the host immune response to this infection is an important first step that should facilitate the development of immunomodulatory agents and vaccines. Cellular immune responses, especi...

The present paper introduces new classes of Stancu–Kantorovich operators constructed in the King sense. For these operators, we establish some convergence results, error estimations theorems and graphical properties approximation for considered, namely, that preserve test functions e0(x)=1 e1(x)=x, e2(x)=x2, as well e1(x)=x e2(x)=x2. class e2(x)=x2 is a genuine generalization introduced by Indr...

BACKGROUND The aim of this study was to investigate whether the anisotropy parameters are helpful in the detection and discrimination of breast cancers, and to determine its value in predicting the risk of cancers. MATERIAL AND METHODS There were 56 patients with 56 lesions (34 malignant, 22 benign) included in the study. DTI was performed in every patient and apparent diffusion coefficient (AD...