Hepatitis B and C are considered as an important health hazard among health care workers (HCWs). These blood borne infections can be transmitted either from HCW to a patient or vice-versa. Both viruses are known to cause hepatitis, cirrhosis and hepatocellular carcinoma. Among these two blood borne infections, HBV is usually more stable in the external environment and is more infectious as comp...

At the 2017 Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle, Washington, hepatitis C virus (HCV) infection was a major focus in the context of HIV-associated liver disease. Well-tolerated direct-acting antiviral (DAA) regimens have enabled effective treatment of the populations that are hardest to cure, including those with decompensated cirrhosis, and many studies exa...

Neutralizing monoclonal antibodies are being found to be increasingly useful in viral infections. In hepatitis B infection, antibodies are proven to be useful for passive prophylaxis. The preS1 region (21-47a.a.) of HBV contains the viral hepatocyte-binding domain crucial for its attachment and infection of hepatocytes. Antibodies against this region are neutralizing and are best suited for imm...

Chronic hepatitis B (CHB) is a major global health problem affecting an estimated 350 million people with more than 786000 individuals dying annually due to complications, such as cirrhosis, liver failure and hepatocellular carcinoma (HCC). Liver transplantation (LT) is considered gold standard for treatment of hepatitis B virus (HBV)-related liver failure and HCC. However, post-transplant vira...

Background Prevention of mother-to-child transmission (MTCT) hepatitis B virus (HBV) involves neonatal immunoprophylaxis, with a birth dose vaccine and immune globulin, provision peripartum antiviral prophylaxis in highly viraemic women. However, access to assays quantify HBV DNA levels remains inadequate resource-poor settings. This study was commissioned by WHO aimed identify the threshold fo...

The management of hepatitis B virus (HBV) infection in pregnancy is complex. Because infection with HBV in infancy often leads to chronic disease, prevention of perinatal or vertical transmission is a major goal. Worldwide, vertical transmission remains the most frequent route of infection, particularly in endemic areas where up to 20% of women of childbearing age may have HBV. These women cons...

We present a case in which an elderly woman diagnosed with a splenic marginal zone lymphoma (MZL) was found to have positive Hepatitis B serology. Link with Hepatitis C virus is well documented but reports of association of Hepatitis B virus (HBV) with splenic marginal zone lymphoma are still emerging. A 69-year-old lady presented with weight loss, pancytopenia and marked splenomegaly. Prior to...

BACKGROUND Pregnant women with Hepatitis B virus HBV represent a major reservoir of the virus in the community. Data regarding the prevalence of HBV in pregnant women and maternal transmission of the virus in Libya are lacking. METHODOLOGY Hepatitis blood samples from 1,500 pregnant women and 1,500 cord blood samples of their neonates delivered at Tripoli Medical Center, Tripoli, were tested ...

BACKGROUND Medical students represent a population that is at high-risk group for acquiring and spreading hepatitis B infection (HBV). AIM This study was designed to evaluate the knowledge and attitudes among male student regarding occupational risks of HBV infection. SUBJECTS AND METHODS During March 2013, a descriptive cross-sectional study was conducted on medical students of AlJouf Univ...