In the course of studying the properties of several viruses pathogenic for suckling mice (Stanley and Hayes, 1950; Stanley et al., 1951), it was found necessary to attempt to purify certain strains to determine if virus, free from large amounts of non-virus protein, could be used in haemagglutination or complement-fixation tests. This paper describes the purification procedures adopted with thr...

Two monoclonal antibodies raised against Sindbis virus were shown to be specific for the envelope glycoprotein E1 by radioimmunoprecipitation (RIP). They had a number of contrasting biological properties. One of them was capable of neutralizing virus infectivity and inhibiting haemagglutination, while the other had no significant neutralizing or haemagglutination-inhibiting capability, but did ...

Inactivated vaccines of Avibacterium paragallinarum provide protection and reduce the economic losses caused by infectious coryza. However, inactivated bacterins provide protection only against the Page serovars included in the vaccine. In this study, we investigated the immunological properties of a functional recombinant haemagglutinin protein (rHagA) derived from a Taiwan isolate strain A9 a...

background and aims: rubella is a contagious viral disease mostly with mild clinical symptoms and often remains undiagnosed. rubella infection may adversely affect pregnancy, especially in the first trimester and this mother to child transmission can cause congenital rubella and may be lead to permanent disability and mortality in children. effective rubella vaccine should be prepared using sui...