Chronic constipation is a common gastrointestinal disorder that effects an estimated 12% to 30% of general population worldwide. Descurainia sophia L. known commonly as flixweed acts as first-line medical treatment for constipation in Iranian traditional medicine. The aim of this study was to assess the efficacy and safety of this remedy for treating functional constipation by standard assessme...

Age-specific arrest rates for the United States at the crime peak of the late 1980s and early 90s are compared to those for 2010. Three key features are explored; (1) The disproportionate decline in adolescent offending; (2) The decline in this age-effect up to age 40; (3) Offenders aged in their 40s who in 2010 offended at higher rates than offenders of that age at crime’s peak. The first two ...

n engl j med 362;17 nejm.org april 29, 201

Constipation is a highly prevalent disorder that affects people regardless of age, race, gender, or socioeconomic status. For many patients, constipation is a chronic condition that reduces quality of life. Chronic constipation also imposes a significant economic burden on the health care system. The treatment of constipation remains problematic for both patients and providers for a variety of ...

OBJECTIVE We aimed to evaluate clinical features and follow-up data of children with functional and secondary constipation. METHODS Hospital records of 335 constipated children were evaluated. Children were divided into 2 groups as functional and secondary, and were compared with regard to clinical and anthropometric data. FINDINGS Of 335 children (M/F 167/168, mean age 4.3±3.5 years) 91% h...

Constipation is a digestive disorder that often occurs in the elderly; its main cause is bowel motility disorder. Treatments for patients with chronic constipation include pharmacotherapy, diet changes, and surgery if other therapies do not offer satisfactory results. We describe 4 patients, 2 men (70 and 65 years old) and 2 women (75 and 66 years old), who were diagnosed with chronic constipat...

Aim: The purpose of this study was to investigate the effects education provided pregnant women with complaints constipation on their constipation-related quality life and severity.Methods: This randomized controlled experimental consisted an intervention group (n:32) a control (n:32). data were collected by using Personal Information Form, Constipation Severity Instrument Patient Assessment Qu...

Chronic constipation is a common disorder in the general population, with higher prevalence in the elderly, and is associated with worse quality of life and with greater health care utilization. Lubiprostone is an intestinal type-2 chloride channel activator that increases intestinal fluid secretion, small intestinal transit, and stool passage. Lubiprostone is currently approved by the US Food ...

Constipation is the most ignored complaint by doctors and unfortunately, it requires urgent management due to the decreased quality of life. Most cases are functional constipation but there is also a great number of constipation due to organic abnormalities. In an attempt to manage the patient properly, we should put our emphasis on excellent knowledge of pathophysiology of constipation.By usin...