نتایج جستجو برای: h5n1

تعداد نتایج: 4735  

2010
Vivi Setiawaty Endang R. Sedyaningsih Tjahyani M. Sudiro Mirna Robert R. van Beest Holle Krisna N. A. Pangesti Fera Ibrahim

Aim Between July 2005 and May 2008, Indonesia reported 133 H5N1 confi rmed human cases with a case fatality proportion of 81%. Fifty-four percent of cases had a history of direct contact with poultry (chickens). Therefore, it is important to defi ne the detection of antibody of H5N1 among people who have intensive contact with poultry have been exposed to H5N1 viruses. Methods We collected sera...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
Y Guan L L M Poon C Y Cheung T M Ellis W Lim A S Lipatov K H Chan K M Sturm-Ramirez C L Cheung Y H C Leung K Y Yuen R G Webster J S M Peiris

Infection with avian influenza A virus of the H5N1 subtype (isolates A/HK/212/03 and A/HK/213/03) was fatal to one of two members of a family in southern China in 2003. This incident was preceded by lethal outbreaks of H5N1 influenza in waterfowl, which are the natural hosts of these viruses and, therefore, normally have asymptomatic infection. The hemagglutinin genes of the A/HK/212/03-like vi...

Journal: :PLoS ONE 2008
Walter R. J. Taylor Bui Nghia Thinh Giang Thuc Anh Peter Horby Heiman Wertheim Niklas Lindegardh Menno D. de Jong Kasia Stepniewska Tran Thuy Hanh Nguyen Duc Hien Ngo Minh Bien Ngo Quy Chau Annette Fox Nghiem My Ngoc Martin Crusat Jeremy J. Farrar Nicholas J. White Nguyen Hong Ha Trinh Thi Lien Nguyen Vu Trung Nicholas Day Nguyen Gia Binh

In the absence of a parenteral drug, oral oseltamivir is currently recommended by the WHO for treating H5N1 influenza. Whether oseltamivir absorption is adequate in severe influenza is unknown. We measured the steady state, plasma concentrations of nasogastrically administered oseltamivir 150 mg bid and its active metabolite, oseltamivir carboxylate (OC), in three, mechanically ventilated patie...

2008
Yuan‐Zheng Qiu Wei‐Dong Yin

Sinovac Biotech started to develop prototype pandemic influenza H5N1 vaccines in March 2004. On 2 April 2008, Sinovac's inactivated, aluminium-adjuvanted, whole-virion prototype pandemic influenza A (H5N1) vaccine (PanFlu) was granted production licensure by the China regulatory authority State Food and Drug Administration. The whole-virion H5N1 vaccine was manufactured in embryonated hens' egg...

2010
Garry W. Lynch Paul W. Selleck Anna-Maree Axell Teena Downton Natalie M. Kapitza Ingrid Boehm Wayne Dyer Ying-Fan Yvonne Wang Sacha Stelzer-Braid William Rawlinson John S. Sullivan

It is necessary to understand whether some humans possess natural humoral-immune protection for avianH5N1 influenza. To broadly assess an exposure naïve cohort we have examined intravenous immunoglobulins (IVIGs) isolated from pools of many thousands of normal Australian blood donations. In studies of the anti-H5N1 antibody potential of these highly purified IVIG therapeutics and of individual ...

2015
Andrew S. Taft Makoto Ozawa Adam Fitch Jay V. Depasse Peter J. Halfmann Lindsay Hill-Batorski Masato Hatta Thomas C. Friedrich Tiago J. S. Lopes Eileen A. Maher Elodie Ghedin Catherine A. Macken Gabriele Neumann Yoshihiro Kawaoka

Avian influenza viruses of the H5N1 subtype pose a serious global health threat due to the high mortality (>60%) associated with the disease caused by these viruses and the lack of protective antibodies to these viruses in the general population. The factors that enable avian H5N1 influenza viruses to replicate in humans are not completely understood. Here we use a high-throughput screening app...

Journal: :Emerging Infectious Diseases 2008
Cristiana Gioia Concetta Castilletti Massimo Tempestilli Paola Piacentini Licia Bordi Roberta Chiappini Chiara Agrati Salvatore Squarcione Giuseppe Ippolito Vincenzo Puro Maria R. Capobianchi Fabrizio Poccia

Avian influenza virus (H5N1) can be transmitted to humans, resulting in a severe or fatal disease. The aim of this study was to evaluate the immune cross-reactivity between human and avian influenza (H5N1) strains in healthy donors vaccinated for seasonal influenza A (H1N1)/(H3N2). A small frequency of CD4 T cells specific for subtype H5N1 was detected in several persons at baseline, and season...

Journal: :Umi medical journal 2023

Latar Belakang: Avian influenza adalah infeksi virus menular yang menyerang unggas, hewan, dan manusia di seluruh dunia. Sebagian besar pada disebabkan oleh tipe A B, sedangkan unggas hanya terinfeksi A.
 Isi: Masa inkubasi umumnya 2 sampai 7 hari, tapi bisa selama 8 9 hari. Gejala klinis ditandai dengan demam tinggi, batuk, gejala saluran pernapasan bagian bawah. World Health Organization...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2009
Haeman Jang David Boltz Katharine Sturm-Ramirez Kennie R Shepherd Yun Jiao Robert Webster Richard J Smeyne

One of the greatest influenza pandemic threats at this time is posed by the highly pathogenic H5N1 avian influenza viruses. To date, 61% of the 433 known human cases of H5N1 infection have proved fatal. Animals infected by H5N1 viruses have demonstrated acute neurological signs ranging from mild encephalitis to motor disturbances to coma. However, no studies have examined the longer-term neurol...

Journal: :The Journal of infectious diseases 2009
Lei Zhou Qiaohong Liao Libo Dong Yang Huai Tian Bai Nijuan Xiang Yuelong Shu Wei Liu Shiwen Wang Pengzhe Qin Min Wang Xuesen Xing Jun Lv Ray Y Chen Zijian Feng Weizhong Yang Timothy M Uyeki Hongjie Yu

BACKGROUND In China, 30 human cases of avian influenza A (H5N1) virus infection were identified through July 2008. We conducted a retrospective case-control study to identify risk factors for influenza H5N1 disease in China. METHODS A questionnaire about potential influenza H5N1 exposures was administered to 28 patients with influenza H5N1 and to 134 randomly selected control subjects matched...

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