During Helicobacter pylori (H. pylori) infection CD4+ T cells in the gastric lamina propria are hyporesponsive and polarized by Th1/Th17 cell responses controlled by Treg cells. We have previously shown that H. pylori upregulates B7-H1 expression on GEC, which, in turn, suppress T cell proliferation, effector function, and induce Treg cells in vitro. In this study, we investigated the underlyin...

we read the paper written by razeghinejad et al. (1), who conducted a study on anti- helicobacter pylori (h. pylori) igg antibody levels in an iranian glaucoma cohort, with considerable interest and based on our original concept (2-5). the authors concluded that a relation between h. pylori infection and primary open-angle glaucoma is not supported by their results, because the aqueous anti- h....

objective: helicobacter pylori is a major etiological agent in gastro-duodenal disorders, and has spread in the world. the prevalence of infection with h. pylori is more than 80% in some populations, but only 10% to 20% of them are infected with this organism. also infection with this pathogen is associated with peptic ulcer disease (pud), gastritis (g), duodenitis (du), and non-ulcer dyspepsi...

BACKGROUND Helicobacter pylori infection is a major cause of gastric diseases. The clinical implications of H. pylori infection in various diseases outside the gastrointestinal system have also been reported, including in some respiratory disorders. In this study, we investigated the seroprevalence of H. pylori in patients with mild to moderate COPD in an Asian country with a high prevalence of...

Background: Risk of recurrent bleeding from Helicobacter pylori-negative ulcers is greater than for H pylori ulcers, but to what degree is unknown. Objective: To determine the risk of rebleeding for peptic ulcers with and without associated H pylori infection. Design: Prospective cohort study in 1 institution over 7 years. Participants: 120 patients had H pylori-negative peptic ulcer bleeding a...

Gastrointestinal disease and colonization by Helicobacter pylori were determined in 36 asymptomatic volunteers and 30 symptomatic individuals undergoing endoscopy and biopsy. Serum antibody immunoglobulin G (IgG) and IgA to H. pylori were measured by enzyme-linked immunosorbent assay. Serum antibody to a cytotoxin produced by H. pylori was detected with a neutralization assay. Serum IgG was 95%...

BACKGROUND Helicobacter pylori infection remains a common problem and previous studies in the Caribbean revealed infection in over 50% of patients undergoing upper endoscopy. OBJECTIVE The present study determined the prevalence of H pylori infection in patients undergoing upper gastrointestinal endoscopy in the Turks and Caicos Islands over a two- year interval. METHODS All patients with u...

Helicobacter pylori (H. pylori) infection is etiologically associated with gastric cancer and peptic ulcer diseases which are both important public health burdens and which could be largely eliminated by H. pylori eradication. However, some investigators urge caution based on the hypothesis that eradication of H. pylori may result in an increase in the incidence of gastroesophageal reflux disea...

BACKGROUND AND AIM The infection of Helicobacter pylori (H. pylori) is acquired in childhood and the prevalence vary greatly in different countries and regions. The study aimed to investigate the characteristics of H. pylori infection among children with gastrointestinal symptoms in Hangzhou, a representative city of eastern China. METHODS A systematic surveillance of H. pylori infection acco...

BACKGROUND/AIMS Helicobacter pylori infection causes gastritis, peptic ulcers and gastric malignancies, and its eradication has been advocated by many groups. We determined the H. pylori carrier status and eradication rates of patients with chronic hepatitis C virus (HCV) infection. METHODS In total, 76 chronically HCV-infected patients were enrolled for comparison with 228 HCV-noninfected, a...