BACKGROUND Frailty can lead towards serious adverse consequences, such as disability. With regard to prevention valid screening instruments are needed to identify frail older people. The aim was to evaluate and compare the psychometric properties of three screening instruments: the Groningen Frailty Indicator (GFI), the Tilburg Frailty Indicator (TFI) and the Sherbrooke Postal Questionnaire (SP...

The ability to acquire large-scale recordings of neuronal activity in awake and unrestrained animals is needed to provide new insights into how populations of neurons generate animal behavior. We present an instrument capable of recording intracellular calcium transients from the majority of neurons in the head of a freely behaving Caenorhabditis elegans with cellular resolution while simultane...

Tracey Day, Cecilia Morgan, Adi Ferrara, and Jim Kublin Welcome to a new edition of the HVTNews, the newsletter of the HIV Vaccine Trials Network. Our newsletter’s mission is to provide timely updates on the science of HIV vaccines, and the science of the HVTN. To that end, this issue features discussions that include innate immunity studies at the HVTN, the possible impact of the RV144 Correla...

A personalized e-learning service provides learning content to fit learners’ individual differences. Learning achievements are influenced by cognitive as well as non-cognitive factors such as mood, motivation, interest, and personal styles. This paper proposes the Learning Caution Indexes (LCI) to detect aberrant learning patterns. The philosophy behind the LCI is that if any non-cognitive fact...

To understand network dynamics of microcircuits in the neocortex, it is essential to simultaneously record the activity of a large number of neurons . In-vivo two-photon calcium imaging is the only method that allows one to record the activity of a dense neuronal population with single-cell resolution . The method consists in implanting a cranial imaging window, injecting a fluorescent calcium ...

Incidence of faecal coliforms in shellfish harvesting areas of the southern coastal district of Karnataka was examined for evaluating the sanitary quality in relation to the seasonal monsoon and river-runoff. Faecal coliforms (FC) counts in seawater, mussel tissue and sediments were highest in monsoon. Geometric mean for FC in sea water was below 14 MPN/100 ml, standard set for “approved area” ...

This paper discusses the measurement of poverty and well-being. A historical overview is given of the last fifty years. This is followed by discussion of three groupings of indicators: those measures based primarily on economic well-being; those based on non-economic well-being and composite indicators. It is argued that the choice of indicator should reflect its purpose and that economic measu...

The spatio-temporal variability of trends in vegetation greenness in dryland areas is a well-documented phenomenon in remote sensing studies at global to regional scales. The underlying causes differ, however, and are often not well understood. Here, we analyzed the trends in vegetation greenness for a semi-arid area in northeastern Brazil (NEB) and examined the relationships between those dyna...

This paper explores temporal aspects of control behavior in order to support the design of systems where functions can be allocated flexibly in time. Dynamic Function Scheduling, an extension of Dynamic Function Allocation approaches, highlights the role of temporal information and temporal reasoning in supervisory control decisions. The microworld experiment presented 30 participants with a su...