The objective of this study was to determine whether use of mupirocin nasal ointment for perioperative eradication of Staphylococcus aureus nasal carriage is effective in preventing the development of surgical site infections (SSIs). A randomized, double-blind, placebo-controlled design was used. Either mupirocin or placebo nasal ointment was applied twice daily to 614 assessable patients from ...

Good hydration is the single most important external factor responsible for optimal wound healing. Unfortunately, available moisture retentive materials, products and devices require a certain expertise for application, are relatively expensive, may be associated with some serious complications and side effects, but most of all are impractical for application over large surface areas. We presen...

Patients undergoing non-ocular surgery under general anesthesia may suffer from ocular complications because of the loss of protective reflexes. Simple taping of the eyelids closed, the instillation of ointments into the conjunctival sac, and the use of protective goggles have been recommended for eye protection. We observed a case of a 6-year-old child undergoing tonsillectomy and adenoidectom...

Present study deals with Topical Drug Delivery system composed of polyherbals including Neem, Tulsi, Aloe and Fenugreek which are having Antifungal and Antibacterial activity in the form of gel, were formulated using gelling agent as Carbopol 934 and was compared with ointment prepared by taking same herbal drugs using emulsifying ointment base B. P. The gels and ointments were evaluated for va...

Indonesia has various beneficial plants species which has not been specifically cultivated yet. One of those plants was Blimbi (Averrhoa bilimbi L.). Blimbi had potential on Staphylococcus aureus and Escherichia coli bacteria as the antibacterial. Its nanoparticle became a carrier which dissolved, trapped, encapsulated, or attached the chemical preparation inside its matrix. This study aimed to...

A 43-year-old woman presented with a widespread morphea, which had its onset three months before. The patient had several plaques of active, pigmented, lilac halo disease on the trunk, arms and thighs. A biopsy confirmed that the patient was suffering from morphea. Therapy with clobetasol propionate ointment 0.05% was introduced, applied twice a day, 5 days a week. After a month, the ointment f...

BACKGROUND The aim of this study was to compare the effect of topical glycerol trinitrate ointment (GTN) with topical diltiazem hydrochloride ointment (DTZ) in the treatment of chronic anal fissure. METHOD Prospectively, 102 patients were treated randomly with either GTN ointment (0.2%) or DTZ ointment (2%) couple of times daily for 12 weeks. RESULTS Forty-five patients (88.2%) in group DTZ...

PURPOSE To compare three different treatment modalities for traumatic corneal abrasions. METHODS We conducted a prospective, randomized, masked, three-arm clinical study of patients presenting with superficial corneal foreign bodies. Treatment modalities were: (1) pressure patching with ofloxacin ointment (patch group, PG, n = 18), (2) therapeutic contact lens with ofloxacin eye drops (contac...