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COVER Confocal light microscopy image of a lateral root emerging from the main root (width: ~130 to 150 micrometers) of a young Arabidopsis thaliana plant (green, nuclei; red, cell walls). Lateral roots initiate deep within the primary (“mother”) root. Their emergence from the mother root is a highly regulated process requiring adjacent cells to shrink and make way for the developing lateral ro...

On the cover: Dynamic change of the localization of FROUNT and CCR5 in CCL4-stimulated cell. Immunofluorescent staining at 20 min after stimulation detects colocalization of FROUNT (red) and CCR5 (green) in both the pseudopodial area and the inner cellular space (colocalization is white). Toda, E., Y. Terashima, T. Sato, K. Hirose, S. Kanegasaki, and K. Matsushima. 2009. FROUNT is a common regu...

www.sciencemag.org SCIENCE VOL 326 23 OCTOBER 2009 493 COVER A three-color mosaic derived from the Moon Mineralogy Mapper (M) near-infrared spectrometer. Orange and pink colors illustrate the distribution of iron-bearing minerals. Green represents the surface brightness at 2.4 micrometers. Blue indicates the presence of small amounts of surficial OH and H 2 O that are most prominent at these vi...

COVER Immunostained fl uorescence microscopy image of a biomarker of endogenous withdrawal (phosphorylated extracellular regulated kinase, red) that increases in mouse spinal cord neurons (green) during opioid receptor blockade (image width: 250 micrometers). Infl ammation or injury to the skin causes μ-opioid receptors to become constitutively active, which leads to long-term relief from chron...

www.sciencemag.org SCIENCE VOL 324 17 APRIL 2009 303 COVER Multiphoton laser scanning images showing cortical (top) and medullary (bottom) portions of a mouse inguinal lymph node. Green spheres represent dendritic cell precursors 5 hours after transfer from bone marrow; B cell follicles are shown in blue; blood vessels and T cells are in red. During development, these precursors migrate through...

Cover photograph: Immunofluorescence microscopy of a mouse placenta at midgestation showing triple staining of amino acid transporter LAT1 (magenta), endothelial marker CD341 (green), and nuclei (cyan). In addition to the mononucleated chorionic trophoblasts, LAT1 is expressed in the syncytiotrophoblasts (two parallel membranous structures) which separate the maternal blood sinusoids and the fe...

labeled tissue section prepared from an embryonic day 13.5 mouse brain. Most migratory interneurons in the developing cerebral cortex express GFP (green) and calbindin (red). Nuclei are counterstained with Draq5 (purple). The accompanying cover video shows the robust migration of cortical interneurons into the developing mouse cerebral cortex. For more information, see the article by Myers et a...

a. To check that the graph is represented correctly, Bob asks Alice to remove all the paper cups covering the endpoints of every edge. This reveals an isomorphism to the original graph, which Bob cannot check efficiently; thus, Bob also removes the paper cups corresponding to the green numbers, revealing the original labelling of the vertices. This reveals nothing about the vertex cover, but al...

147 News From the American Heart Association B1 Meetings Calendar B2 On the cover: Piece (1 mm) of a rat heart embedded in a fibrin gel and cultured for seven days under conditions of hypoxia (1% O2) and inclusion of 10 ng/ml basic Fibroblast Growth Factor. Emerging capillary-like sprouts are characterized in-gel by endothelial specific FITC-coupled lectin G. simplicifolia (green fluorescent). ...