The aim of this research was to evaluate the effect of bismuth subgallate on wound healing. In 40 Wistar rats, two standard wounds (3.5 mm x 2 mm) were made using a biopsy punch on the back of each animal. Test wounds were filled with bismuth subgallate and control wounds with 0.9% saline. At 1, 4, 7, 11 and 18 days, the qualitative evolution of the granulation tissue morphology was observed an...

Wegener granulomatosis (WG) is a multisystemic disorder characterised by granulomatous inflammation of the respiratory system. The growing of proliferative tissue towards the larynx and trachea may cause airway obstruction on account of subglottic stenosis. In this situation, the surgical goal is to eliminate the airway obstruction by providing natural airway anatomy. While mild lesions do not ...

The plasma and tissue concentration of ascorbic acid (AA) is reduced in diabetes. This study was designed to investigate the mechanism and significance of this phenomenon. The low plasma AA concentration of diabetic rats can be normalized by dietary AA supplement (20-40 mg/day), a dosage approximately equal to the maximal synthetic rate of this substance in the rats. Treatment of diabetic rats ...

cells with less fluorescent nuclei. The corneal epithelial cellular autofluorescence was most likely due to nicotinamide adenine dinucleotide phosphate. At 200 μm, the collagen pattern at the wound is irregularly arranged, which is in sharp contrast to the orthogonal packing of adjacent lamella found in normal stroma (Figure 1H). At imaging depths of 400 μm and beyond, regions lacking in SHG co...

To the Editor, With this letter we provide an update on a case of eumycetoma caused by Madurella mycetomatis in a mare that we previously reported on [1]. The mare was euthanized in May 2013 at age 9 years following a case of acute colic. Throughout her life, the mare foaled three times and had one miscarriage. During the 6 years between the first diagnosis and euthanasia, abundant granulation ...

the effect of prepared ayurvedic formulation was evaluated on excision and incision wound models in rats. the wound-healing activity was assessed by the rate of period of epithelialization and skin-breaking strength. histological study of the granulation tissue was carried out to know the extent of collagen formation in the wound tissue. the ayurvedic formulation prepared was then promoted for ...

BACKGROUND Endoscopic sinus surgery (ESS) has become the widely accepted procedure for the treatment of medically refractory chronic rhinosinusitis and nasal polyps. Nasal packing is usually placed after ESS to prevent synechia formation and postoperative bleeding and to support wound healing. The aim of this study was to evaluate the effects of three different nasal packing materials [Vaseline...

Actin cytoskeletal polymerization is associated with a pro-proliferative, pro-survival state. We hypothesized that the actin polymerization of wound cells is increased in the presence of wound matrix attachment and is decreased after disruption of this attachment. Musculocutaneous flap and wound splinting models were used to investigate the effect of wound matrix attachment on the actin cytoske...