The perplexing clinical course of a 23-year-old black male with isolated gonococcal pulmonary valvular endocarditis is presented. M-mode echocardiography provided the first clue to the presence of pulmonary valvular vegetations and the proper diagnosis. Since Neisseria gonorrhea appears to have a particular affinity for the pulmonary valve, the presence of isolated pulmonary valvular endocardit...

The perplexing clinical course of a 23-year-old black male with isolated gonococcal pulmonary valvular endocarditis is presented. M-mode echocardiography provided the first clue to the presence of pulmonary valvular vegetations and the proper diagnosis. Since Neisseria gonorrhea appears to have a particular affinity for the pulmonary valve, the presence of isolated pulmonary valvular endocardit...

In an open prospective study, single oral doses of norfloxacin (800 mg) and thiamphenicol (2.5 g) were used to treat, respectively, 122 and 46 consecutive patients with uncomplicated gonorrhea. Neisseria gonorrhoeae was eradicated from 119 (97.5%) patients treated with norfloxacin and from 35 (76.0%) patients treated with thiamphenicol. Norfloxacin treatment failure was not related to drug resi...

Gonorrhea (aka "the clap," or "the drip") is caused by sexually transmitted Neisseria gonorrhoeae--a Gram-negative diplococcus. One of the most common reportable diseases in the United States, gonorrhea frequently affects sexually active adolescents. Approximately 30% of the 350,000 annual cases involve 15to 19-year-olds. (That percentage is thought to be an underestimate!) Those most often inf...

1. Adolescents (15–19 years of age) and young adults (20–24 years of age) account for the majority of new cases of gonorrhea reported each year. Gonococcal infections in postpubertal females are commonly asymptomatic. Complications such as pelvic inflammatory disease (PID) and disseminated gonococcal infection (DGI) occur more often in females, probably because of delays in diagnosis and treatm...

Gonorrhea may become untreatable, and new treatment options are essential. Verified resistance to spectinomycin is exceedingly rare. However, we describe a high-level spectinomycin-resistant (MIC, >1,024 μg/ml) Neisseria gonorrhoeae strain from Norway with a novel resistance mechanism. The resistance determinant was a deletion of codon 27 (valine) and a K28E alteration in the ribosomal protein ...

An SIS/SAS model of gonorrhea transmission in a men-seeking-men (MSM) system is presented in this paper to study the impact of education on the dynamics of gonorrhea prevalence. Education affects behaviors that may fall into two categories– prevention and disease status awareness. Stability conditions for the disease free equilibrium and endemic equilibrium are determined along with an analytic...

We present a case of a 22-year-old man with isolated neck pain due to pharyngeal gonorrhea.