It is now known that removal of the olfactory bulbs increases basal gonadotropin secretion and prevents short-photoperiod-induced testicular regression in Syrian hamsters. The experiments described in the present paper were an attempt to determine which neuronal systems associated with the olfactory bulbs are responsible for this influence on the reproductive neuroendocrine axis. In the first e...

of GnRH receptor and gonadotropin subunit gene expression were measured by quantitative PCR.­ Levels of gene expression for the GnRH receptor and gonadotropin subunits decreased following treatment with the GnRH antagonist in pituitaries of gilts from the Index and Control lines; however, these values remained unchanged in pituitar-ies from Meish­an gilts. Identification of unique genetic chang...

background: gonadotropin releasing hormone conjugate (gnrh-bsa) raises antibodies against biologically active gonadotropin releasing hormone (gnrh) which affects body weight, gonadosomatic indices (gsi) and sperm quality in male mice. objective: the objective of this experimental investigation is to develop an effective and reliable hormonal immunocontraceptive vaccine to suppress spermatogenes...

Nuclear receptors typically bind to DNA as homodimers or heterodimers, but increasing numbers of orphan receptors have been identified that bind DNA as monomers.

Seasonal breeding is widespread in vertebrates and involves sequential development of the gonads, onset of breeding activities (e.g. cycling in females) and then termination resulting in regression of the reproductive system. Whereas males generally show complete spermatogenesis prior to and after onset of breeding, females of many vertebrate species show only partial ovarian development and ma...