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Acidic pH inside cells indicates cellular dysfunctions such as cancer. Therefore, the development of optical pH sensors for measuring and imaging intracellular pH is a demanding challenge. The available pH-sensitive probes are vulnerable to e.g. photobleaching or autofluorescence background in biological materials. Our approach circumvents these problems due to near infrared excitation and upco...

The recreational use of 3,4-methyl​enedioxy​methylamphetamine (MDMA) remains consistently high on a global level. This reinforces the importance early, rapid and accurate detection MDMA. work reports novel development rapid, ultrasensitive selective immunofluorescence nanobiosensor probe for To develop nanoprobe, heavy metal-free AuZnFeSeS alloyed quantum dots (QDs) were synthesized coated with...

Freestanding Nanowires In article number 2200948, Juliane Koch and co-workers have electrically characterized the bottom-up grown freestanding nanowires using a four-point nanoprobe method. Due to its very high spatial resolution, conduction channels are identified at nanowire base. This finding will impact on optimization of electrical performance for solar cells water splitting.

We have developed an optical chamber for studying the effect of swelling or shrinking of a gel on the translational diffusion of fluorescent nanoprobes embedded in the gel. On one side of the chamber, the gel is in contact with a hydrating or dehydrating polymeric solution through a porous membrane, allowing control of the rate of hydration or dehydration of the gel. On the other side, a laser ...

Current and future capabilities of X-ray spectromicroscopy are discussed based on coherence-limited imaging methods which will benefit from the dramatic increase in brightness expected from a diffraction-limited storage ring (DLSR). The methods discussed include advanced coherent diffraction techniques and nanoprobe-based real-space imaging using Fresnel zone plates or other diffractive optics ...

Load-displacement curves measured during indentation experiments on thin films depend on non-homogeneous intrinsic film microstructure and residual stress gradients as well as on their changes during indenter penetration into the material. To date, microstructural changes and local stress concentrations resulting in plastic deformation and fracture were quantified exclusively using numerical mo...

We have developed a ratiometric time-gated luminescence sensory system for in vivo imaging of hypochlorous acid (HClO) by preparing a dual-emissive nanoarchitecture of europiumand terbiumcomplex-modified silica nanoparticles. The design of this nanoarchitecture is based on our new finding that the strong, long-lived luminescence of the b-diketonate–Eu complex can be rapidly and selectively quen...

We have developed a ratiometric time-gated luminescence sensory system for in vivo imaging of hypochlorous acid (HClO) by preparing a dual-emissive nanoarchitecture of europium- and terbium-complex-modified silica nanoparticles. The design of this nanoarchitecture is based on our new finding that the strong, long-lived luminescence of the β-diketonate-Eu3+ complex can be rapidly and selectively...