Kidney weight was significantly decreased in hypothyroidism (induced by Na131I administration) and increased in hyperthyroidism (induced by thyroxine treatment) as compared to control in female Wistar rats. The tissue lipid peroxidation level remained unchanged in hyperthyroid rats but significantly increased in hypothyroid rats. Superoxide dismutase was decreased in both experimental groups bu...

Radical scavenging activity of ethanolic extract of Trianthema triquetra root was investigated against CCl4 in rats. The rats were treated with T. triquetra (100 mg, 200 mg/kg b.w.) for a period of 7 days. Antihepatotoxic effect was studied by assaying the activities of thiobarbituric acid (TBARS), reduced glutathione (GSH), glutathione peroxidase (GPx),catalase (CAT), super oxide dismutase (SO...

Background: Regular exercise can alleviate oxidative stress. There are no studies examining changes in this variable as a result of an intense acute taekwondo (TKD) exercise. Objectives: We aimed to investigate the effect one bout TKD on superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), total antioxidant capacity (TAC), and malondialdehyde (MDA) adolescent female taekwon...

Vigorous physical activity is a movement that produces excessive free radicals due to leakage of electrons from the mitochondrial transport system. The body's antioxidant system reduced inability defenses reduce production resulting in oxidative stress, so it requires supply antioxidants outside body such as Virgin Coconut Oil (VCO). purpose this study determine effect VCO administration on mal...

The alleviative effect of procyanidins extracted from the lotus seedpod (LSPC) on oxidative stress in various tissues was evaluated by determining the activities of the antioxidant enzymes and the content of reduced glutathione (GSH) in heart, liver, lung, kidney, skeletal muscle, and serum in aged rats. Aging led to antioxidant deficit in various tissues in this study, which is confirmed by re...

This study compares changes in the pro-oxidant production and buffering capacity in young and aged skeletal muscle after exposure to chronic repetitive loading (RL). The dorsiflexors from one limb of young and aged rats were loaded 3 times/week for 4.5 weeks using 80 maximal stretch-shortening contractions per session. RL increased H2O2 in tibialis anterior muscles of young and aged rats and de...

Abstract Background In silico studies further provided predictive binding properties of selected ligands for inhibition target protein. the study, molecular poses Cucurbitacin-E and antioxidant enzymes (glutathione-S-transferase (GST), superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), peroxidase (GPx) acetylcholinesterase (AChE) Galleria mellonella were determined in silic...

Background: According to the international diabetes federation, 629 million adults will suffer from by 2045. Wet cupping therapy is a combination of bleeding and dry has been used in traditional medicine as complementary for diabetes. Limonene was shown have both antioxidant antidiabetic activity but its potential alongside other treatments not thoroughly explored. Objectives: Although wet-cupp...

For imitating the active site of antioxidant selenoenzyme glutathione peroxidase (GPx), an artificial enzyme selenosubtilisin was employed as a scaffold for reconstructing substrate glutathione (GSH) specific binding sites by a bioimprinting strategy. GSH was first covalently linked to selenosubtilisin to form a covalent complex GSH-selenosubtilisin through a Se-S bond, then the GSH molecule wa...

Oxidative stress is one of the key mechanisms responsible for liver damage and disease progression in non-alcoholic steatohepatitis (NASH). Antioxidants try to combat the oxidative stress and minimise the oxidative stress. In this study, the comparative effect of pioglitazone, quercetin and hydroxy citric acid on lipid peroxidation and antioxidants in experimentally induced NASH has been studie...