Present study examines biological effects of 2.45 GHz microwave radiation in Parkes strain mice. Forty-day-old mice were exposed to CW (continuous wave) microwave radiation (2 h/day for 30 days). Locomotor activity was recorded on running wheel for 12 days prior to microwave exposure (pre-exposure), 7 days during the first week of exposure (short-term exposure) and another 7-day spell during th...

The hepatoprotective activity of crude aqueous extract of Zingiber officinale leaves (ZOL), Zingiberacae, was evaluated, using CCl4 induced hepatic damage in male Wistar albino rats. Various biochemical parameters like serum glutamic pyruvate transaminase (SGPT), serum glutamic oxaloacetate transaminase (SGOT) and total bilirubin were studied. The aqueous ZOL extract afforded significant protec...

Recent research data have shown that systemic administration of pyruvate and oxaloacetate causes an increased brain-to-blood glutamate efflux. Since increased release of glutamate during epileptic seizures can lead to excitotoxicity and neuronal cell death, we tested the hypothesis that glutamate scavenging mediated by pyruvate and oxaloacetate systemic administration could have a neuroprotecti...

The study was conducted to screen for the phytochemicals constituents of bark of Saraca asoca (Roxb.), one of the folk medicinal plants found in West Bengal, Bangladesh and Sri Lanka. The acute and subacute toxicity of methanolic extract of S. asoca bark on mice was studied. Phytochemical analysis of S. asoca (bark) methanolic extract revealed the presence of high percentage of flavonoids and r...

A new flavonoid C-glycoside, kaempferol 8-C-beta-galactoside, along with twelve known glycosidic flavonoids was isolated from the aqueous methanolic extract of Solanum elaeagnifolium Cav. (Solanaceae), by conventional chromatographic methods; their structure elucidation was achieved using UV, ESI-MS, and NMR spectral analyses. Groups of six mice were administered S. elaeagnifolium extracts at 2...

We implemented a nationwide population-based study in Taiwan to compare the physical and biochemical parameters, diet and exercise lifestyles, and prevalences of diabetes, hyperlipidemia, and hypertension between males and females, and to clarify the determinants of diabetes, hyperlipidemia, and hypertension in Taiwan. In this cross-sectional study, 7,578 subjects were selected from the general...

Copyright  2014 irjpbs The aim of this work is to study the hepatoprotective effect of polyherbal formulations contains some Indian medicinal plant. The three different herbal formulations obtained from different medicinal plant extracts were evaluated for hepatoprotective in rats by induced liver damage by paracetamol. Paracetamol (3g/kg, p.o) was administered a single dose to induce hepatoto...

This study was aimed at the synthesis of few xanthone derivatives containing 1,4-dioxane ring system. The reaction of 3,4-dihydroxy xanthone derivatives (3a-c) with ethylene dibromide and epichlorohydrin under approriate reaction conditions afforded xanthone derivatives containing 1,4-dioxane ring system (4a-e). The structures of the synthesized compounds were confirmed on the basis of their ch...

CONTEXT Previous studies have shown that Spirulina platensis Gomont (Phormidiaceae) (SP) extract has beneficial effects on many disease conditions. The putative protective effects of SP were investigated in diabetic rats. OBJECTIVE The current study investigates the antioxidant effects of SP in diabetic Wistar rats. MATERIALS AND METHODS Alloxan monohydrate (150 mg/kg body weight) was intra...