نتایج جستجو برای: glucuronosyltransferase

تعداد نتایج: 2005  

2004
Liang Lijun Akira Matsunaga Kazuki Kijima Emi Shirahata Hiroko Izumino Kiyoshi Hayasaka

Address for Correspondence:Kiyoshi Hayasaka, Department of Pediatrics, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan We present two patients with idiopathic nephrotic syndrome who showed temporary indirect hyperbilirubinemia during the course of treatment with immunosuppressant drugs and/or steroids. We analyzed the gene of the bilirubin uridine-diphosphate ...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 1997
F P Guengerich A Parikh E F Johnson T H Richardson C von Wachenfeldt J Cosme F Jung C P Strassburg M P Manns R H Tukey M Pritchard S Fournel-Gigleux B Burchell

This article is a report on a symposium held at the March 1997 meeting of the American Society for Pharmacology and Experimental Therapeutics in San Diego. Current developments in the heterologous expression of cytochrome P450, NADPH-cytochrome P450 reductase, glutathione transferase, and UDP-glucuronosyltransferase enzymes are described. Systems include bacteria, insect cells, and transient an...

Journal: :Environmental Health Perspectives 1994
M Strolin Benedetti P Dostert

Animal studies have demonstrated that the mouse and rabbit are far more responsive to the inductive properties of rifamycin derivatives than the rat and guinea pig. The rat hepatic cytochrome P450 system seems to be resistant to the action of rifampicin unless very high doses are used. Mouse hepatic microsomal mixed-function oxidase activity is markedly increased by repeated dosing with rifampi...

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