Some plant extracts showed the ability to retard the diffusion of glucose across the dialysis tube. The present study was designed to investigate the effect of aqueous and ethanolic extracts of Teucrium polium (T. polium) on glucose movement across the dialysis tube. The T. polium powder was dissolved in ethanol and distilled water. Then glucose was added to make a final concentration of 0.2 - ...

Preimplantation mouse embryos utilize pyruvate preferentially during the early cleavage stages before switching to glucose at around the time of compaction. This switch in substrate preference has been studied using a non-invasive ultramicrofluorometric analytical technique on single mouse embryos. On the basis of transport kinetic studies and inhibition by phloretin, cytochalasin B and sugar a...

Glucose is an important fuel for contracting muscle, and normal glucose metabolism is vital for health. Glucose enters the muscle cell via facilitated diffusion through the GLUT4 glucose transporter which translocates from intracellular storage depots to the plasma membrane and T-tubules upon muscle contraction. Here we discuss the current understanding of how exercise-induced muscle glucose up...

Both glucose administration and extracellular volume expansion augment urinary calcium and magnesium excretion. While volume expansion also augments sodium excretion, glucose induces an antinatriuresis. To examine the interrelationships of volume expansion and of glucose administration on sodium, calcium, and magnesium excretion, the effects of glucose were evaluated during clearance studies in...

Zone diameters for anidulafungin by disk diffusion for 139 isolates of C. parapsilosis were compared with MICs by NCCLS M27-A2 broth microdilution. The comparison was poor unless the disks were prepared by dissolving anidulafungin in 1% dimethyl sulfoxide plus 0.1% Tween 80 and testing on Mueller-Hinton agar flooded with glucose and methylene blue.

Although urea transport is receiving increased attention in mammalian systems, very little is known about urea transport in fish tissues. This study examined mechanisms of urea transport in red blood cells and hepatocytes from the lesser spotted dogfish (Scyliorhinus canicula), Atlantic stingray (Dasyatis sabina), turbot (Scopthalmus maximus), redfish (Scianops ocellatus), gulf toadfish (Opsanu...

Transport of glucose across the muscle cell membrane is an important rate-limiting step in glucose uptake and is a site of metabolic regulation (l-7). The process in muscle exhibits the following properties. It is freely reversible and accelerated in both directions by insulin (8) and anoxia (9, 10). The process shows substrate stereospecificity (8, 1 I), saturation kinetics of the Michaelis-Me...

A novel gene, FSY1, encoding a permease involved in active fructose uptake by a proton symport mechanism in the type strain of Saccharomyces carlsbergensis has been isolated. Fsy1p is only distantly related to the Hxt proteins that mediate facilitated diffusion of glucose and fructose in Saccharomyces cerevisiae and related species.

Direct activation of the fat cell n-glucose transport system by the lectin concanavalin A was studied using a rapid filtration procedure which monitors 3-O-[3H]methylglucose uptake in isolated brown fat cells. Transport of this nonmetabolized D-glucose analogue, which occurs by facilitated diffusion, was linear for 5 or more min, temperature-dependent, and inhibited by unlabeled n-glucose, phlo...

Abstract Diabetes is one of the most devastating global diseases with an ever-increasing number patients. Achieving persistent glycemic control in a painless and convenient way unmet goal for diabetes management. Insulin therapy commonly utilized treatment usually relies on patient self-injection. This not only impairs patient’s quality life fails to precisely blood glucose level but also bring...